Evidence map›Paper›PMID 22189941›Full record

ArticleAmerican journal of hypertension2012

Spousal caregiving and incident hypertension.

Benjamin D Capistrant, J Robin Moon, M Maria Glymour

Open access · bronzeAbstract read
In one paragraph

Article in American journal of hypertension, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
9.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 75 citations in OpenAlex.

  1. Trial
  2. Article
  3. Association between caregiving duration and hypertension among family caregivers: the TMM CommCohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  4. Article
  5. Article
  6. Article
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  8. A Call to Integrate Measures of Environmental Context into Research on Maternal Brain Health.International journal of environmental research and public health · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. A systematic review comparing cardiovascular disease among informal carers and non-carers.International journal of cardiology. Cardiovascular risk and prevention · 2023
    Review
  16. Article
  17. Article
  18. From Burden to Depressive Symptoms in Informal Caregivers during the COVID-19 Pandemic: A Path Analysis.International journal of environmental research and public health · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Benjamin D CapistrantDepartment of Society, Human Development, and Health, Harvard School of Public Health, Boston, Massachusetts, USA. bcapistr@hsph.harvard.edu
J Robin Moon
M Maria Glymour
Harvard University · US

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
CVD Epidemiology Training Program in Behavior, the Environment and Global HealthT32HL098048 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Goodarz Danaei, ERIC B RIMM · 2009 to 2026
$6.9M
Functional Impairment from Stroke: an Exploratory Study of DisparitiesR21AG034385 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI GLYMOUR, MEDELLENA MARIA · 2010 to 2011
$352k
NHLBI NIH HHS T32 HL098048NHLBI NIH HHS T32-HL098048-01NIA NIH HHS R21 AG034385NIA NIH HHS U01 AG009740NIA NIH HHS U01AG009740NICHD NIH HHS R24 HD050924
6 · The paper itself

Abstract

backgroundCaring for one's spouse has been associated with poor health, including risk of cardiovascular disease (CVD) onset and mortality. However, few studies have assessed the risk of incident hypertension associated with spousal caregiving. This paper investigates this association in a large, nationally representative sample of American older adults.

methodsMarried, hypertension-free, Health and Retirement Study (HRS) respondents aged 50+ in 2000, (n = 5,708) were followed up to 8 years (1,708 new self-reported hypertension diagnoses). Current caregiving exposure was defined as assisting a spouse with instrumental or basic activities of daily living (IADLs) 14+ h/week; we define providing ≥14 h/week of care at two consecutive biennial surveys as "long-term caregiving." We used inverse probability weighted discrete-time hazard models with time-updated exposure and covariates to estimate effects of current and long-term caregiving on incident hypertension. We tested for effect modification by race, gender, and recipient memory illness. Sensitivity analyses restricted to respondents whose spouses had care needs.

resultsAfter adjusting for demographic, socioeconomic, and health factors, (including risk behaviors, comorbid conditions, and self-rated health), current caregiving significantly predicted hypertension incidence (risk ratio (RR) = 1.36, 95% confidence interval (CI): 1.01, 1.83). For long-term caregivers, there was significant evidence of risk of hypertension onset associated with caregiving (RR = 2.29, 95% CI: 1.17, 4.49). The risk of hypertension onset associated with both current and long-term caregiving did not vary by race, gender, or recipient memory illness diagnosis. Sensitivity analyses supported the primary findings.

conclusionsProviding IADL care to a spouse significantly predicted hypertension onset in a nationally representative sample of US adults.

Indexed as

CaregiversSpousesActivities of Daily LivingAgedCardiovascular DiseasesFemaleFollow-Up StudiesHumansHypertensionMaleMemory DisordersMiddle AgedOdds RatioStress, Psychological

Identifiers

PMID22189941
PMCPMC3836043
OpenAlexW1980472026

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.