Evidence map›Paper›PMID 22189052›Full record

Trial reportAddictive behaviors2012

Co-occurring marijuana use is associated with medication nonadherence and nonplanning impulsivity in young adult heavy drinkers.

Erica N Peters, Robert F Leeman, Lisa M Fucito, Benjamin A Toll, William R Corbin, Stephanie S O'Malley

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Addictive behaviors, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05090995 (A Photoplethysmography Sensor-based Personalized Feedback Intervention for Heavy-drinking Young Adults Targeting Heart Rate Variability, Resting Heart Rate, and Sleep), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05090995 nacompletednot on this mapstarted 2022, after this paper: background citation

A Photoplethysmography Sensor-based Personalized Feedback Intervention for Heavy-drinking Young Adults Targeting Heart Rate Variability, Resting Heart Rate, and Sleep

TypeinterventionalSponsorYale UniversityRan2022 to 2023Enrolled60ConditionsHeavy Drinking, Harmful, Use, AlcoholArmsBehavioral Self-Management and Feedback, Behavioral Self-Management
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Medical Comorbidity and Complications.Child and adolescent psychiatric clinics of North America · 2016
    Review
  11. Article
  12. Alcohol increases impulsivity and abuse liability in heavy drinking women.Experimental and clinical psychopharmacology · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Erica N PetersYale University School of Medicine, Department of Psychiatry, One Long Wharf Drive, Box 18, New Haven, CT 06511, USA. erica.peters@yale.edu
Robert F Leeman
Lisa M Fucito
Benjamin A Toll
William R Corbin
Stephanie S O'Malley
Yale University · USArizona State University · USYale Cancer Center · US

Funding

Research Training Fellowship in Substance use and Addiction (RTFSA)T32DA007238 · NIDA · YALE UNIVERSITY · PI BRIAN D. KILUK, ISMENE L. PETRAKIS · 1988 to 2026
$5.7M
Naltrexone for Heavy Drinking in Young AdultsR01AA016621 · NIAAA · YALE UNIVERSITY · PI O'MALLEY, STEPHANIE S · 2007 to 2011
$3.0M
Improving Alcoholism TreatmentK05AA014715 · NIAAA · YALE UNIVERSITY · PI O'MALLEY, STEPHANIE S · 2004 to 2013
$2.1M
New Approaches to Smoking Cessation in Heavy DrinkersK23AA020000 · NIAAA · YALE UNIVERSITY · PI FUCITO, LISA M · 2011 to 2016
$755k
Difficulties with Self-Control and High-Risk Alcohol Use in Young AdultsK01AA019694 · NIAAA · YALE UNIVERSITY · PI LEEMAN, ROBERT F · 2010 to 2014
$705k
NIAAA NIH HHS K01 AA019694NIAAA NIH HHS K05 AA014715NIAAA NIH HHS K23 AA020000NIAAA NIH HHS K23-AA020000NIAAA NIH HHS L30 AA018621NIAAA NIH HHS R01 AA016621NIAAA NIH HHS R01-AA016621NIDA NIH HHS T32 DA007238NIDA NIH HHS T32-DA007238
6 · The paper itself

Abstract

Few studies have examined the co-occurrence of alcohol and marijuana use in clinical samples of young adults. The present study investigated whether co-occurring marijuana use is associated with characteristics indicative of a high level of risk in young adult heavy drinkers. Individuals between the ages of 18 and 25 years (N=122) participated in an ongoing 8-week randomized clinical trial that tested the efficacy of placebo-controlled naltrexone plus brief individual counseling to reduce heavy drinking. At intake participants completed self-report assessments on alcohol consumption, alcohol-related negative consequences, motivation to reduce drinking, trait impulsivity, expectancies for alcohol-induced disinhibition, use of cigarettes, and history of medication nonadherence. In univariate tests heavy drinkers with and without co-occurring marijuana use did not differ on alcohol consumption, most alcohol-related negative consequences, and motivation to reduce drinking. In multivariate tests controlling for demographic characteristics, co-occurring heavy alcohol and marijuana use was significantly associated with nonplanning impulsivity (β=2.95) and a history of both unintentional (adjusted odds ratio [aOR]=3.30) and purposeful (aOR=3.98) nonadherence to medication. Findings suggest that young adult heavy drinkers with co-occurring marijuana use exhibit a high-risk clinical profile and may benefit from interventions that increase adherence to medications.

Indexed as

AdolescentAdultAlcohol DeterrentsAlcohol-Related DisordersAnalysis of VarianceCombined Modality TherapyCounselingFemaleHumansImpulsive BehaviorMaleMarijuana SmokingMedication AdherenceMotivationNaltrexonePatient SatisfactionAlcohol DeterrentsNaltrexone

Identifiers

PMID22189052
PMCPMC3288288
OpenAlexW2003910086

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.