ArticleEuropean journal of epidemiology2012
Intergenerational change and familial aggregation of body mass index.
Article in European journal of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Body mass index in parents and their adult offspring: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2024Pooled it
- Trial
- Maternal weight during pregnancy and risk of childhood acute lymphoblastic leukemia in offspring.Leukemia · 2025Article
- Association of Paternal BMI and Diet During Pregnancy with Offspring Birth Measures: The STEPS Study.Nutrients · 2025Article
- Tracing Obesity From Parents to Adult Offspring: The Tromsø Study 1994-2016.Journal of obesity · 2025Article
- Predicting higher child BMI z-score and obesity incidence in Malaysia: a longitudinal analysis of a dynamic cohort study.BMC public health · 2024Article
- Is obesity more likely among children sharing a household with an older child with obesity? Cross-sectional study of linked National Child Measurement Programme data and electronic health records.BMJ paediatrics open · 2024Article
- Time to Consider the "Exposome Hypothesis" in the Development of the Obesity Pandemic.Nutrients · 2022Review
- Temporal Trends and Familial Clustering of Ideal Cardiovascular Health in Parents and Offspring Over the Life Course: An Investigation Using The Framingham Heart Study.Journal of the American Heart Association · 2020Article
- Parental body mass index and blood pressure are associated with higher body mass index and blood pressure in their adult offspring: a cross-sectional study in a resource-limited setting in northern Peru.Tropical medicine & international health : TM & IH · 2018Article
- Maternal and Early Childhood Determinants of Women's Body Size in Midlife: Overall Cohort and Sibling Analyses.American journal of epidemiology · 2017Article
- Perceptions of diet, physical activity, and obesity-related health among black daughter-mother pairs in Soweto, South Africa: a qualitative study.BMC public health · 2016Article
- Article
- Epigenomics, gestational programming and risk of metabolic syndrome.International journal of obesity (2005) · 2015Review
- Parental Midlife Body Shape and Association with Multiple Adult Offspring Obesity Measures: North West Adelaide Health Study.PloS one · 2015Article
- The Generation R Study: Biobank update 2015.European journal of epidemiology · 2014Article
- Early origins of chronic obstructive lung diseases across the life course.European journal of epidemiology · 2014Review
- Trends in parent-child correlations of childhood body mass index during the development of the obesity epidemic.PloS one · 2014Article
- The Rotterdam Study: 2014 objectives and design update.European journal of epidemiology · 2013Article
- Maternal and grandmaternal obesity and environmental factors as determinants of daughter's obesity.Nutrition research and practice · 2013Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The relationship between parental BMI and that of their adult offspring, when increased adiposity can become a clinical issue, is unknown. We investigated the intergenerational change in body mass index (BMI) distribution, and examined the sex-specific relationship between parental and adult offspring BMI. Intergenerational change in the distribution of adjusted BMI in 1,443 complete families (both parents and at least one offspring) with 2,286 offspring (1,263 daughters and 1,023 sons) from the west of Scotland, UK, was investigated using quantile regression. Familial correlations were estimated from linear mixed effects regression models. The distribution of BMI showed little intergenerational change in the normal range (<25 kg/m(2)), decreasing overweightness (25-<30 kg/m(2)) and increasing obesity (≥30 kg/m(2)). Median BMI was static across generations in males and decreased in females by 0.4 (95% CI: 0.0, 0.7) kg/m(2); the 95th percentile increased by 2.2 (1.1, 3.2) kg/m(2) in males and 2.7 (1.4, 3.9) kg/m(2) in females. Mothers' BMI was more strongly associated with daughters' BMI than was fathers' (correlation coefficient (95% CI): mothers 0.31 (0.27, 0.36), fathers 0.19 (0.14, 0.25); P = 0.001). Mothers' and fathers' BMI were equally correlated with sons' BMI (correlation coefficient: mothers 0.28 (0.22, 0.33), fathers 0.27 (0.22, 0.33). The increase in BMI between generations was concentrated at the upper end of the distribution. This, alongside the strong parent-offspring correlation, suggests that the increase in BMI is disproportionally greater among offspring of heavier parents. Familial influences on BMI among middle-aged women appear significantly stronger from mothers than fathers.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.