Evidence map›Paper›PMID 22187253›Full record

Trial reportYonsei medical journal2012

Lipid-emulsion propofol less attenuates the regulation of body temperature than micro-emulsion propofol or sevoflurane in the elderly.

Cheol Won Jeong, Jin Ju, Dae Wook Lee, Seong Heon Lee, Myung Ha Yoon

Registry-linked trialOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Yonsei medical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02502877 (Core Temperature Variations During Midazolam vs Propofol Sedation for Neuraxial Anesthesia), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02502877 nacompletednot on this mapstarted 2015, after this paper: background citation

Core Temperature Variations During Midazolam vs Propofol Sedation for Neuraxial Anesthesia

TypeinterventionalSponsorHospital da Luz, PortugalRan2015 to 2016Enrolled27ConditionsBody Temperature Changes, AnesthesiaArmsMidazolam, Propofol, Standard, SpotOn
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Observational
  2. Article
  3. Factors associated with unintended perianesthesia hypothermia.Proceedings (Baylor University. Medical Center) · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cheol Won JeongDepartment of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju, Korea.
Jin Ju
Dae Wook Lee
Seong Heon Lee
Myung Ha Yoon
Chonnam National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAnesthesia and surgery commonly cause hypothermia, and this caused by a combination of anesthetic-induced impairment of thermoregulatory control, a cold operation room environment and other factors that promote heat loss. All the general anesthetics markedly impair normal autonomic thermoregulatory control. The aim of this study is to evaluate the effect of two different types of propofol versus inhalation anesthetic on the body temperature. MATERIALS AND

methodsIn this randomized controlled study, 36 patients scheduled for elective laparoscopic gastrectomy were allocated into three groups; group S (sevoflurane, n=12), group L (lipid-emulsion propofol, n=12) and group M (micro-emulsion propofol, n=12). Anesthesia was maintained with typical doses of the study drugs and all the groups received continuous remifentanil infusion. The body temperature was continuously monitored after the induction of general anesthesia until the end of surgery.

resultsThe body temperature was decreased in all the groups. The temperature gradient of each group (group S, group L and group M) at 180 minutes from induction of anesthesia was 2.5 ± 0.6°C, 1.6 ± 0.5°C and 2.3 ± 0.6°C, respectively. The body temperature of group L was significantly higher than that of group S and group M at 30 minutes and 75 minute after induction of anesthesia, respectively. There were no temperature differences between group S and group M.

conclusionThe body temperature is maintained at a higher level in elderly patients anesthetized with lipid-emulsion propofol.

Indexed as

AgedAgingAnesthesia, GeneralAnesthetics, CombinedAnesthetics, InhalationAnesthetics, IntravenousBody TemperatureBody Temperature RegulationFat Emulsions, IntravenousFemaleHumansMaleMethyl EthersMiddle AgedPropofolSevofluraneAnesthetics, CombinedAnesthetics, InhalationAnesthetics, IntravenousFat Emulsions, IntravenousMethyl EthersPropofolSevoflurane

Identifiers

PMID22187253
PMCPMC3250313
OpenAlexW2011978063

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.