ArticleJournal of neurology2012
Screening for balance disorders in mildly affected multiple sclerosis patients.
Article in Journal of neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 39 citations in OpenAlex.
- Eyes closed single-leg stance test detects subtle sensorimotor decline in early multiple sclerosis.Scientific reports · 2026Article
- Balance Impairments in People with Early-Stage Multiple Sclerosis: Boosting the Integration of Instrumented Assessment in Clinical Practice.Sensors (Basel, Switzerland) · 2022Article
- Postural Control in Relapsing-Remitting Multiple Sclerosis.International archives of otorhinolaryngology · 2022Article
- Balance Testing in Multiple Sclerosis-Improving Neurological Assessment With Static Posturography?Frontiers in neurology · 2020Article
- A comparison of balance control during stance and gait in patients with inflammatory and non-inflammatory polyneuropathy.PloS one · 2018Article
- Balance Changes in Patients With Relapsing-Remitting Multiple Sclerosis: A Pilot Study Comparing the Dynamics of the Relapse and Remitting Phases.Frontiers in neurology · 2018Article
- Use of Nintendo Wii Balance Board for posturographic analysis of Multiple Sclerosis patients with minimal balance impairment.Journal of neuroengineering and rehabilitation · 2017Article
- Quantification of postural stability in minimally disabled multiple sclerosis patients by means of dynamic posturography: an observational study.Journal of neuroengineering and rehabilitation · 2017Observational
- The dual task-cost of standing balance affects quality of life in mildly disabled MS people.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2016Article
- Detection of postural sway abnormalities by wireless inertial sensors in minimally disabled patients with multiple sclerosis: a case-control study.Journal of neuroengineering and rehabilitation · 2015Article
- Strategies used by individuals with multiple sclerosis and with mild disability to maintain dynamic stability during a steering task.Experimental brain research · 2014Article
- Understanding balance differences in individuals with multiple sclerosis with mild disability: an investigation of differences in sensory feedback on postural control during a Romberg task.Experimental brain research · 2014Article
- The clinical relevance of force platform measures in multiple sclerosis: a review.Multiple sclerosis international · 2013Article
- Association of Postural Sway with Disability Status and Cerebellar Dysfunction in People with Multiple Sclerosis: A Preliminary Study.International journal of MS careArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple sclerosis (MS) patients often complain about balance problems when Romberg's test and tandem gait are normal. The aim of the study was to determine if measures of trunk sway taken during a battery of stance and gait tasks could be used to detect subclinical balance disorders. We recorded trunk angular sway in the pitch and roll directions from 20 MS patients (EDSS 1.4 ± 0.5) and 20 age- and gender-matched healthy controls (HCs), during 12 stance and gait tasks. We filmed 22 subjects simultaneously. Two neurologists assessed the videos, deciding whether task performance was pathological. Sway measures were significantly different between patients and HCs in eight out of 12 balance tasks. The most significant differences between MS patients and HCs were pitch angle range standing on one leg with eyes open on a firm surface (mean 3.13° vs. 2.09°, p = 0.005), and on a foam support surface (mean 6.24° vs. 2.96°, p = 0.006), pitch velocity range walking 8 m with eyes closed (mean 75.5 vs. 50.2°/s, p < 0.001) and pitch velocity range walking 3 m on heels (mean 85.37 vs. 60.9°/s, p = 0.002). Multivariate analysis revealed a model with three tasks which detected balance disorders in 84% of the MS patients and 90% of the HCs correctly. The neurologists achieved accuracies of 30% for the MS patients and 82% for the HCs. Using trunk sway measures during stance and gait tasks is a sensitive screening method for balance problems in MS patients, and is more accurate than assessment by trained neurologists.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.