ReviewLung2012
Cough hypersensitivity syndrome is an important clinical concept: a pro/con debate.
Review in Lung, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06669897 (Validation of a Questionnaire to Measure Cough Severity in Patients With Chronic Cough), which is not on this map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Validation of a Questionnaire to Measure Cough Severity in Patients With Chronic Cough
Who cites it
15 citing papers in PubMed, 41 citations in OpenAlex.
- Efficacy and tolerability of a polysaccharide-resin-honey based cough syrup as compared to carbocysteine syrup for children with colds: a randomized, single-blinded, multicenter study.World journal of pediatrics : WJP · 2017Trial
- Cough Reflex Sensitivity in Asthmatic Children.Physiological research · 2020Article
- Association of cough hypersensitivity with tracheal TRPV1 activation and neurogenic inflammation in a novel guinea pig model of citric acid-induced chronic cough.The Journal of international medical research · 2018Article
- Effect of viral upper respiratory tract infection on cough reflex sensitivity.Journal of thoracic disease · 2014Review
- Review
- Review
- Changing the paradigm for cough: does 'cough hypersensitivity' aid our understanding?Asia Pacific allergy · 2014Review
- Antitussive drugs--past, present, and future.Pharmacological reviews · 2014Review
- Chronic cough hypersensitivity syndrome.Cough (London, England) · 2013Article
- Refractory chronic cough, or the need to focus on the relationship between the larynx and the esophagus.Cough (London, England) · 2013Article
- Estrogen effects in allergy and asthma.Current opinion in allergy and clinical immunology · 2013Review
- Article
- Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology.Cough (London, England) · 2012Article
- A 54 year-old man with a chronic cough--Following referral: a secondary care perspective from the UK.Primary care respiratory journal : journal of the General Practice Airways Group · 2012Article
- Evaluation methods and influencing factors of cough sensitivity.Therapeutic advances in respiratory diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The major etiologies of chronic cough are generally accepted to consist of upper airway cough syndrome (formerly postnasal drip syndrome), eosinophilic airway inflammation (asthma, nonasthmatic eosinophilic bronchitis), and gastroesophageal reflux disease (GERD). However, only a small percentage of patients with these very common conditions suffers from chronic cough. Furthermore, acute cough due to viral upper respiratory tract infection (URI) is almost always a transient, self-limited condition, yet in a small subgroup of patients, URI heralds the onset of chronic, refractory cough. The cough hypersensitivity syndrome has been proposed to explain the occurrence of chronic cough in a subgroup of patients exposed to the same putative triggers as the vast majority of the population in whom chronic cough does not result. Although conceptually the cough hypersensitivity syndrome may be intellectually satisfying, differences of opinion remain as to whether this newly recognized entity is of clinical significance, i.e., useful for the treatment of patients suffering from chronic cough. The Third American Cough Conference, held in New York in June 2011, provided an ideal forum for the debate of this issue between two internationally recognized authorities in the field of cough.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.