ReviewLancet (London, England)2012
Myocarditis.
Review in Lancet (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03525639 (Cardiac Magnetic Resonance Evaluation of Myocardial Inflammation Persistence After Acute Myocarditis), which is not on this map. Cited by 413 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cardiac Magnetic Resonance Evaluation of Myocardial Inflammation Persistence After Acute Myocarditis: Prognostic Relevance
Who cites it
413 citing papers in PubMed, 5 syntheses or guidelines pooled it, 725 citations in OpenAlex.
- Pooled it
- Immunosuppressive therapy in patients with biopsy-proven inflammatory myocardial disease: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Revisiting Secondary Dilative Cardiomyopathy.International journal of molecular sciences · 2025Pooled it
- Diagnostic Value of Cardiovascular Magnetic Resonance T1 and T2 Mapping in Acute Myocarditis: A Systematic Literature Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- SBC Guideline on the Diagnosis and Treatment of Patients with Cardiomyopathy of Chagas Disease - 2023.Arquivos brasileiros de cardiologia · 2023Guideline
- Therapeutic Ultrasound in Cardiovascular Medicine: Applications of Low-intensity Pulsed Ultrasound and Ultrasound-targeted Microbubble Destruction.Cardiovascular drugs and therapy · 2026Review
- B-Cell Immune Responses in Myocarditis: Mechanisms, B-Cell Receptor Repertoire, and Clinical Translation.Cells · 2026Review
- Accurate pathologic classification of aggressive myocarditis improves insights into patient precise medicine.Fundamental research · 2026Article
- Deep learning-derived left ventricular circumferential strain for cardiac MRI diagnosis of acute myocarditis with preserved ejection fraction.The international journal of cardiovascular imaging · 2026Article
- Dissecting myocardial and systemic drivers of cardiac dysfunction in the murine CVB3 myocarditis model using microRNA-guided viral detargeting.Basic research in cardiology · 2026Article
- Acute Myocarditis: From Pathophysiology to Risk-Stratified Management-A Clinical Review.European journal of clinical investigation · 2026Review
- Review
- Veno-arterial ECMO in fulminant myocarditis: a retrospective single-center case series.BMC cardiovascular disorders · 2026Observational
- Non-invasive diagnostic model for myocarditis using cardiac magnetic resonance radiomics.Quantitative imaging in medicine and surgery · 2026Article
- Distinguishing myocarditis from perimyocardial syndromes in children presenting to the emergency department: a biomarker-based approach.BMC emergency medicine · 2026Article
- Biological potential and mechanisms of Brain-Expressed X-linked family proteins in cancers: an updated review.Journal of advanced research · 2026Review
- Immunophenotypes and prognosis in autoimmune cardiovascular disease: a narrative review from clonal hematopoiesis to myocarditis, microvascular angina, and HFpEF.Annals of medicine and surgery (2012) · 2026Review
- Macrophages of the heart: Homeostasis and disease.Biomedical journal · 2026Review
- Effects of Cardiac Remodeling and Altered Mechanics on Cardiac Outcomes in Fulminant Myocarditis in Children: Insight from a Longitudinal Pilot Study.Pediatric cardiology · 2026Article
- Quantitative Cardiac MRI in COVID-19 Vaccine-Related Versus Other Types of Myocarditis: A Korean Multicenter Study.Journal of Korean medical science · 2026Article
353 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Myocarditis is an underdiagnosed cause of acute heart failure, sudden death, and chronic dilated cardiomyopathy. In developed countries, viral infections commonly cause myocarditis; however, in the developing world, rheumatic carditis, Trypanosoma cruzi, and bacterial infections such as diphtheria still contribute to the global burden of the disease. The short-term prognosis of acute myocarditis is usually good, but varies widely by cause. Those patients who initially recover might develop recurrent dilated cardiomyopathy and heart failure, sometimes years later. Because myocarditis presents with non-specific symptoms including chest pain, dyspnoea, and palpitations, it often mimics more common disorders such as coronary artery disease. In some patients, cardiac MRI and endomyocardial biopsy can help identify myocarditis, predict risk of cardiovascular events, and guide treatment. Finding effective therapies has been challenging because the pathogenesis of chronic dilated cardiomyopathy after viral myocarditis is complex and determined by host and viral genetics as well as environmental factors. Findings from recent clinical trials suggest that some patients with chronic inflammatory cardiomyopathy have a progressive clinical course despite standard medical care and might improve with a short course of immunosuppression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.