ArticleCirculation journal : official journal of the Japanese Circulation Society2012
Region- and condition-dependence of the membrane and Ca2+ clocks in the sinus node.
Article in Circulation journal : official journal of the Japanese Circulation Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
- Chronotropic incompetence presenting as sudden sinus slowing during exercise stress test: the pathophysiological mechanisms.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The results presented by Shinohara et al(1) suggests that both the membrane clock and the Ca(2+) clock contribute to sinus node automaticity. Which is dominant depends on the region within the sinus node and the condition of the SNS. When you change the way you look at things, the things you look at change. This new hypothesis is very attractive, because it combines the membrane and Ca(2+) clocks. In fact, supporting data have been reported by the same parties.(11,12) Supportive studies by others are warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.