SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2012
Does minimally invasive esophagectomy (MIE) provide for comparable oncologic outcomes to open techniques? A systematic review.
Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Minimally invasive oesophagectomy versus open esophagectomy for resectable esophageal cancer: a meta-analysis.World journal of surgical oncology · 2016Pooled it
- Pooled it
- Evaluation of safety profile of thoracoscopic esophagectomy for T1bN0M0 cancer using data from JCOG0502: a prospective multicenter study.Surgical endoscopy · 2015Trial
- Trial
- National trends in operative approach to esophagectomy: utilization rates, outcomes, and overall survival.Surgical endoscopy · 2025Article
- Article
- Comparison of Clinical Efficacy Between Da Vinci Robot-Assisted Ivor Lewis Esophagectomy and McKeown Esophagectomy for Middle and Lower Thoracic Esophageal Cancer: A Multicenter Propensity Score-Matched Study.Annals of surgical oncology · 2023Article
- Minimally invasive surgery for gastro-oesophageal junction adenocarcinoma: Current evidence and future perspectives.World journal of gastrointestinal oncology · 2023Review
- Neoadjuvant Chemotherapy Compared with Surgery for Oesophageal Carcinoma: A Retrospective Study and Missing Evidence.Journal of Cancer · 2023Article
- Minimally invasive Ivor-Lewis esophagectomy for esophageal cancer.Turk gogus kalp damar cerrahisi dergisi · 2022Article
- Comparative analysis of long-term oncologic outcomes for minimally invasive and open Ivor Lewis esophagectomy after neoadjuvant chemoradiation: a propensity score matched observational study.Journal of cardiothoracic surgery · 2021Observational
- Learning curve for minimally invasive oesophagectomy of oesophageal cancer and survival analysis.Journal of cardiothoracic surgery · 2021Article
- Improved Quality of Care and Efficiency Do Not Always Mean Cost Recovery After Minimally Invasive Ivor Lewis Esophagectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Minimally invasive total adventitial resection of the cardia for tumours of the oesophagogastric junction.Langenbeck's archives of surgery · 2021Article
- Thirty years of esophageal cancer surgery in Oulu University Hospital.Journal of thoracic disease · 2021Article
- Robot-Assisted Esophagectomy After Neoadjuvant Chemoradiation-Current Status and Future Prospects.Indian journal of surgical oncology · 2020Review
- Minimally Invasive Ivor Lewis Esophagectomy (MILE): technique and outcomes of 100 consecutive cases.Surgical endoscopy · 2020Article
- Early Respiratory Impairment and Pneumonia after Hybrid Laparoscopically Assisted Esophagectomy-A Comparison with the Open Approach.Journal of clinical medicine · 2020Article
- Postoperative adjuvant chemotherapy versus chemoradiotherapy for node-positive esophageal squamous cell carcinoma: a propensity score-matched analysis.Radiation oncology (London, England) · 2020Article
- Surgical principles for optimal treatment of esophagogastric junction adenocarcinoma.Annals of gastroenterological surgery · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study is to compare minimally invasive esophagectomy (MIE) and open techniques with respect to oncologic outcomes through analysis of the extent of lymph node clearance, number of lymph nodes retrieved, oncologic stage, and 5-year mortality. METHODOLOGY: A systematic review of the literature review was conducted using MEDLINE, PubMed, EMBASE, and the Cochrane databases (1950-2011), and evaluated all comparative studies. Comparison between the open and MIE/hybrid MIE (HMIE) groups was possible with data being available for direct comparison.
resultsAfter careful review, 17 case-control studies with 1,586 patients having an esophagectomy were included in this systematic review. The median (range) number of lymph nodes found in the MIE, open and HMIE groups were 16 (5.7-33.90), 10 (3-32.80) and 17 (17-17.15), of which there was significance between the MIE and open groups (p=0.03) but not significant between MIE versus HMIE (p=0.25). There was no statistical significance in pathologic stage between open, MIE and HMIE groups. Generally, there were good short-term (30 day) survival rates between all three groups. The open group had 5-year survival rates between 16% and 57% compared to the MIE group 12.5%-63% (p=0.33). Overall 5-year survival was found to be not significant between open group and MIE (p=0.93). MIE does not appear on statistical evidence to present any survival advantage.
conclusionThe evidence of this study suggests that MIE is equivalent to standard open esophagectomy in achieving similar oncological outcomes. Further randomised controlled trials are required to provide for a higher level of evidence.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.