ArticleJournal of gastroenterology2012
Risk factors for pancreatic stone formation in autoimmune pancreatitis over a long-term course.
Article in Journal of gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 47 citations in OpenAlex.
- Challenges for clinicians treating autoimmune pancreatitis: Current perspectives.World journal of clinical cases · 2023Review
- Review
- Autoimmune pancreatitis with pancreatic calculi and pseudocyst: a case report.The Journal of international medical research · 2021Article
- The Role of Endoscopic Ultrasound-guided Drainage for Autoimmune Pancreatitis-associated Pancreatic Cysts: A Report of Five Cases and a Literature Review.Internal medicine (Tokyo, Japan) · 2018Review
- Long-term outcomes of autoimmune pancreatitis.World journal of gastroenterology · 2016Review
- Transpapillary biliary stenting is a risk factor for pancreatic stones in patients with autoimmune pancreatitis.Endoscopy international open · 2016Article
- Extracorporeal shock wave lithotripsy treatment of pancreatic stones complicated with advanced stage autoimmune pancreatitis.BMC gastroenterology · 2015Article
- Type 1 autoimmune pancreatitis and IgG4-related sclerosing cholangitis is associated with extrapancreatic organ failure, malignancy, and mortality in a prospective UK cohort.The American journal of gastroenterology · 2014Article
- Autoimmune pancreatitis can develop into chronic pancreatitis.Orphanet journal of rare diseases · 2014Article
- Amendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 II. Extrapancreatic lesions, differential diagnosis.Journal of gastroenterology · 2014Article
- Recent advances in the diagnosis and management of autoimmune pancreatitis: similarities and differences in Japan and Korea.Gut and liver · 2013Article
- Type 1 autoimmune pancreatitis can transform into chronic pancreatitis: a long-term follow-up study of 73 Japanese patients.International journal of rheumatology · 2013Article
- Evolution in the diagnosis and treatment of autoimmune pancreatitis: experience from a single tertiary care center.International journal of clinical and experimental pathology · 2013Observational
- Chronic pancreatitis.Current opinion in gastroenterology · 2012Review
- Recent advances in autoimmune pancreatitis.Frontiers in physiology · 2012Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAutoimmune pancreatitis (AIP) has the potential to progress to a chronic state that forms pancreatic stones. The aim of this study was to clarify the risk factors underlying pancreatic stone formation in AIP.
methodsSixty-nine patients with AIP who had been followed for at least 3 years were enrolled for evaluation of clinical and laboratory factors as well as computed tomography and endoscopic retrograde cholangiopancreatography findings.
resultsDuring the course of this study, increased or de novo stone formation was seen in 28 patients, who were defined as the stone-forming group. No stones were observed in 32 patients, who were defined as the non-stone-forming group. Nine patients who had stones at diagnosis but showed no change during the course of this study were excluded from our cohort. Univariate analysis revealed no significant differences in clinical or laboratory factors associated with AIP-specific inflammation between the two groups. However, pancreatic head swelling (P = 0.006) and narrowing of both Wirsung's and Santorini's ducts in the pancreatic head region (P = 0.010) were significantly more frequent in the stone-forming group. Furthermore, multivariate analysis identified Wirsung and Santorini duct narrowing at diagnosis as a significant independent risk factor for pancreatic stone formation (OR 4.4, P = 0.019).
conclusionsA primary risk factor for pancreatic stone formation in AIP was narrowing of both Wirsung's and Santorini's ducts, which most presumably led to pancreatic juice stasis and stone development.
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