ArticleEuropean archives of psychiatry and clinical neuroscience2012
Prevalence of the metabolic syndrome in unipolar major depression.
Article in European archives of psychiatry and clinical neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 77 citations in OpenAlex.
- The prevalence and related factors of metabolic syndrome in outpatients with first-episode drug-naive major depression comorbid with anxiety.Scientific reports · 2021Trial
- Metabolic syndrome improvement in depression six months after prescribing simple hygienic-dietary recommendations.BMC research notes · 2014Trial
- ADHD and metabolic syndrome: behavioral and weight-related pathways to cardiovascular risk.European archives of psychiatry and clinical neuroscience · 2026Article
- Prevalence and factors associated with dyslipidemia in patients with first hospitalization for major depressive disorder: a large sample cross-sectional study.BMC psychiatry · 2024Article
- Association of subclinical hypothyroidism with metabolic syndrome and its components among outpatients with first-episode drug-naïve major depressive disorder: a large-scale cross-sectional study.European archives of psychiatry and clinical neuroscience · 2024Article
- Prevalence and factors associated with metabolic syndrome in first hospitalization for major depression disorder patients.Scientific reports · 2023Article
- Personalized Medicine of Omega-3 Fatty Acids in Depression Treatment in Obese and Metabolically Dysregulated Patients.Journal of personalized medicine · 2023Review
- Prevalence and clinical correlates of abnormal lipid metabolism in first-episode and drug-naïve patients with major depressive disorder with abnormal glucose metabolism.Scientific reports · 2023Article
- Effects of elevated emotional symptoms on metabolic disease development: a 10-year follow-up study.Frontiers in psychiatry · 2023Article
- Depression and Cardiovascular Disease: The Viewpoint of Platelets.International journal of molecular sciences · 2020Review
- Employers With Metabolic Syndrome and Increased Depression/Anxiety Severity Profit Most From Structured Exercise Intervention for Work Ability and Quality of Life.Frontiers in psychiatry · 2020Article
- Association between serum lipid levels, osteoprotegerin and depressive symptomatology in psychotic disorders.European archives of psychiatry and clinical neuroscience · 2019Article
- Psychobiological factors of resilience and depression in late life.Translational psychiatry · 2019Review
- Metabolic syndrome and depressive symptoms among rural Northeast general population in China.BMC public health · 2017Article
- Exercise therapy improves aerobic capacity of inpatients with major depressive disorder.Brain and behavior · 2016Article
- Depression, anxiety disorders, and metabolic syndrome in a population at risk for type 2 diabetes mellitus.Brain and behavior · 2015Article
- Hepatocyte nuclear factor 4 alpha is a key factor related to depression and physiological homeostasis in the mouse brain.PloS one · 2015Article
- Exploring the Link between the Components of Metabolic Syndrome and the Risk of Depression.BioMed research international · 2015Article
- Effects of oxidative stress on fatty acid- and one-carbon-metabolism in psychiatric and cardiovascular disease comorbidity.Acta psychiatrica Scandinavica · 2014Review
- Metabolic syndrome among psychiatric outpatients with mood and anxiety disorders.BMC psychiatry · 2014Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous studies on the association between affective disorders and the metabolic syndrome yielded inconclusive results. Therefore, we examined the prevalence of the metabolic syndrome in 230 men and women with unipolar major depressive disorder during inpatient treatment and compared it to 1,673 subjects from primary care from a similar region in northern Germany. We used the AHA/NHBLI criteria to determine the rate of metabolic syndrome (MetS) and each single criterion of MetS in both groups. The age-standardized prevalence of MetS was 2.4× as high in patients with major depressive disorder (MDD) compared with data from comparison subjects (41.0% vs. 17.0%). With respect to the single criteria, elevations were found in MDD patients for fasting glucose and triglycerides in both genders, and waist circumference in women. Men in the patient and the comparison groups were found to have higher rates of increased fasting glucose and triglycerides than women in the respective groups. Factors associated with the MetS in MDD patients comprise body mass index and the severity of depression. Our results demonstrate an increased prevalence of the MetS in men and women with MDD. Interventions for the frequently untreated metabolic abnormalities and careful screening for physical health conditions among people with MDD are warranted.
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