ReviewNature reviews. Nephrology2011
Diuretic use in renal disease.
Review in Nature reviews. Nephrology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04982874 (Bioequivalence Study of Furosemide in Indonesian Healthy Volunteers), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bioequivalence Study of Furosemide in Indonesian Healthy Volunteers
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.
- Pooled it
- Efficacy and safety of oral tolvaptan in patients undergoing hemodialysis: a Phase 2, double-blind, randomized, placebo-controlled trial.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Trial
- From mechanisms to clinical practice: a review of diuretic therapy in pediatric nephrology.Pediatric nephrology (Berlin, Germany) · 2026Review
- QSPR analysis of the drugs used to treat renal failure and its complications using degree and modified reverse degree indices.Scientific reports · 2026Article
- Association of estimated glomerular filtration rate and in-hospital mortality in patients hospitalized for heart failure: a retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Diuretic Use Among Hemodialysis Patients in Lebanon: A Multicenter Observational Retrospective Study.International journal of nephrology · 2025Article
- Diuretic Treatment in Heart Failure: A Practical Guide for Clinicians.Journal of clinical medicine · 2024Review
- Diuretic prescriptions in the first year of haemodialysis: international practice patterns and associations with outcomes.Clinical kidney journal · 2024Article
- Effects of furosemide, acetazolamide and amiloride on renal cortical and medullary tissue oxygenation in non-anaesthetised healthy sheep.Experimental physiology · 2024Article
- Association of diuretics with falls and wrist fractures: a Mendelian randomization study.Frontiers in public health · 2024Article
- Diuretics and the kidney.BJA education · 2022Review
- Blood pressure management and renal protection: Revisiting hypertensive nephropathy.Journal of the Chinese Medical Association : JCMA · 2021Review
- Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis.Nature communications · 2021Article
- Contribution of Uptake and Efflux Transporters to Oral Pharmacokinetics of Furosemide.ACS omega · 2020Article
- Hyperkalemia and Acute Kidney Injury with Spironolactone Use Among Patients with Heart Failure.Mayo Clinic proceedings · 2020Article
- Drugs Commonly Applied to Kidney Patients May Compromise Renal Tubular Uremic Toxins Excretion.Toxins · 2020Article
- Diagnosis and Management of Pulmonary Hypertension in Patients With CKD.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020Review
- An in-vitro assay using human spermatozoa to detect toxicity of biologically active substances.Scientific reports · 2019Article
- Simulating a virtual population's sensitivity to salt and uninephrectomy.Interface focus · 2018Article
- Type 2 Diabetes and Thiazide Diuretics.Current diabetes reports · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diuretics are agents commonly used in diseases characterized by excess extracellular fluid, including chronic kidney disease, the nephrotic syndrome, cirrhosis and heart failure. Multiple diuretic classes, including thiazide-type diuretics, loop diuretics and K(+)-sparing diuretics, are used to treat patients with these diseases, either individually or as combination therapies. An understanding of what determines a patient's response to a diuretic is a prerequisite to the correct use of these drugs. The response of patients with these diseases to diuretics, which is related to the dose, is best described by a sigmoid curve whose contour can become distorted by any of the several sodium-retaining states that are directly or indirectly associated with renal disease. Diuretic actions are of considerable importance to patients who have renal disease, as their effective use assists in extracellular fluid volume control, reducing excretion of protein in urine and lessening the risk of developing hyperkalemia. Diuretic-related adverse events that involve the uric acid, Na(+) and K(+) axes are not uncommon; therefore the clinician must be vigilant in looking for biochemical disturbances. As a result of diuretic-related adverse events, clinicians must be resourceful in the dose amount and frequency of dosing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.