Evidence map›Paper›PMID 22183448›Full record

ArticleThe Journal of pediatrics2012

Occurrence and timing of childhood overweight and mortality: findings from the Third Harvard Growth Study.

Aviva Must, Sarah M Phillips, Elena N Naumova

Abstract readComparative Study
In one paragraph

Article in The Journal of pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. The Cardiovascular Disease (CVD) Risk Continuum from Prenatal Life to Adulthood: A Literature Review.International journal of environmental research and public health · 2022
    Review
  8. Article
  9. An Overview of the Obese-Asthma Phenotype in Children.International journal of environmental research and public health · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Observational
  19. Article
  20. Obesity and Autism.Pediatrics · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aviva MustDepartment of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA. aviva.must@tufts.edu
Sarah M Phillips
Elena N Naumova

Funding

Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI GREENBERG, ANDREW S, PERISSI, VALENTINA · 1992 to 2021
$25.0M
IMPACT OF CHILDHOOD OBESITY AND GROWTH ON MORTALITYR29HD036017 · NICHD · TUFTS UNIVERSITY BOSTON · PI MUST, AVIVA · 1998 to 2002
$340k
NICHD NIH HHS R29 HD036017NIDDK NIH HHS P30 DK046200
6 · The paper itself

Abstract

objectiveTo assess the mortality experience of participants in the Third Harvard Growth Study (1922-1935) who provided ≥ 8 years of growth data. STUDY

designA total of 1877 participants provided an average of 10.5 body mass index measurements between age 6 and 18 years. Based on these measurements, the participants were classified as ever overweight or ever >85th percentile for height in childhood. Age at peak height velocity was used to indicate timing of overweight relative to puberty. Relative risks of all-cause and cause-specific mortality according to measures of childhood growth were estimated using Cox proportional hazards survival analysis.

resultsFor women, ever being overweight in childhood increased the risks of all-cause and breast cancer death; the risk of death from ischemic heart disease was increased in men. Men with a first incidence of overweight before puberty were significantly more likely to die from ischemic heart disease; women in the same category were more likely to die from all causes and from breast cancer.

conclusionWe find evidence of long-term effects of having ever been overweight, with some evidence that incidence before puberty influences the pattern of risk.

Indexed as

Cause of DeathAdolescentAgedAge FactorsAge of OnsetAnthropometryBody Mass IndexBreast NeoplasmsCardiovascular DiseasesChildCohort StudiesComorbidityConfidence IntervalsFemaleFollow-Up StudiesHumans

Identifiers

PMID22183448
PMCPMC3397161

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.