Evidence map›Paper›PMID 22183412›Full record

ReviewAdvances in experimental medicine and biology2012

A tale of two kinases in rods and cones.

Shoji Osawa, Ellen R Weiss

Open access · greenAbstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Mechanisms of Location Bias in G Protein-Coupled Receptors.Handbook of experimental pharmacology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Phosphorylation at Serine 21 in G protein-coupled receptor kinase 1 (GRK1) is required for normal kinetics of dark adaption in rod but not cone photoreceptors.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shoji OsawaDepartment of Cell and Developmental Biology, The University of North Carolina at Chapel Hill, CB# 7090, 108 Taylor Hall, Chapel Hill, NC 27599, USA.
Ellen R Weiss
University of North Carolina at Chapel Hill · US

Funding

VISION RESEARCHP30EY005722 · NEI · DUKE UNIVERSITY · PI Vadim Y Arshavsky · 1985 to 2026
$19.3M
P30-Core Grant for Vision Research Core CP30EY006360 · NEI · EMORY UNIVERSITY · PI BOATRIGHT, JEFFREY H · 1986 to 2025
$15.3M
DESENSITIZATION OF CONE VISUAL SIGNALING PATHWAYSR01EY012224 · NEI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WEISS, ELLEN RUTH · 2000 to 2019
$5.4M
The Role of Phosphorylation in Photoreceptor Cell BiologyR21EY019758 · NEI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WEISS, ELLEN RUTH · 2009 to 2010
$405k
NEI NIH HHS EY019758NEI NIH HHS EY072224NEI NIH HHS EY5722NEI NIH HHS P30 EY005722NEI NIH HHS P30 EY006360NEI NIH HHS R01 EY012224NEI NIH HHS R21 EY019758
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dark AdaptationG-Protein-Coupled Receptor Kinase 1G-Protein-Coupled Receptor KinasesHumansRetinal Cone Photoreceptor CellsRetinal DiseasesRetinal Rod Photoreceptor CellsRhodopsinG-Protein-Coupled Receptor Kinase 1G-Protein-Coupled Receptor KinasesGRK1 protein, humanGRK7 protein, humanRhodopsin

Identifiers

PMID22183412
PMCPMC3632502
OpenAlexW154905187

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.