Evidence map›Paper›PMID 22183385›Full record

ArticleAdvances in experimental medicine and biology2012

Modeling the structural consequences of BEST1 missense mutations.

Karina E Guziewicz, Gustavo D Aguirre, Barbara Zangerl

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advances in experimental medicine and biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Bestrophinopathy: An RPE-photoreceptor interface disease.Progress in retinal and eye research · 2017
    Review
  3. Bestrophin 1 and retinal disease.Progress in retinal and eye research · 2017
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Karina E GuziewiczSection of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Ryan Veterinary Hospital, 3900 Delancey Street, Room 2020, Philadelphia, PA 19104, USA.
Gustavo D Aguirre
Barbara Zangerl
Hospital of the University of Pennsylvania · US

Funding

MODELS OF HEREDITY RETINAL DEGENERATIONR01EY006855 · NEI · UNIVERSITY OF PENNSYLVANIA · PI GUSTAVO David AGUIRRE, William A. Beltran · 1992 to 2026
$20.7M
Scientific TransparencyP30EY001583 · NEI · UNIVERSITY OF PENNSYLVANIA · PI Qi N Cui · 1985 to 2026
$19.5M
Translational Research for Retinal Degeneration TherapiesR01EY017549 · NEI · UNIVERSITY OF PENNSYLVANIA · PI BELTRAN, WILLIAM A. · 2007 to 2024
$14.1M
CANINE MODELS OF HEREDITARY RETINAL DEGENERATIONSU01EY006855 · NEI · UNIVERSITY OF PENNSYLVANIA · PI AGUIRRE, GUSTAVO DAVID · 1986 to 1992
–
NEI NIH HHS EY06855NEI NIH HHS EY17549NEI NIH HHS P30 EY001583NEI NIH HHS P30EY-001583NEI NIH HHS R01 EY006855NEI NIH HHS R01 EY017549
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Models, ChemicalAnimalsBestrophinsChloride ChannelsComputer SimulationDisease Models, AnimalDog DiseasesDogsEye ProteinsHumansMembrane ProteinsMutation, MissenseStructure-Activity RelationshipVitelliform Macular DystrophyWaterBEST1 protein, humanBestrophinsChloride ChannelsEye ProteinsMembrane ProteinsWater

Identifiers

PMID22183385
PMCPMC3951900
OpenAlexW1707408107

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.