Evidence map›Paper›PMID 22183353›Full record

ArticleAdvances in experimental medicine and biology2012

Development and validation of a canine-specific profiling array to examine expression of pro-apoptotic and pro-survival genes in retinal degenerative diseases.

Sem Genini, William A Beltran, Gustavo D Aguirre

Abstract readValidation Study
In one paragraph

Article in Advances in experimental medicine and biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sem GeniniDepartment of Clinical Studies, University of Pennsylvania, Section of Ophthalmology, School of Veterinary Medicine, 3900 Delancey Street, Philadelphia, PA 19104, USA.
William A Beltran
Gustavo D Aguirre

Funding

MODELS OF HEREDITY RETINAL DEGENERATIONR01EY006855 · NEI · UNIVERSITY OF PENNSYLVANIA · PI GUSTAVO David AGUIRRE, William A. Beltran · 1992 to 2026
$20.7M
Translational Research for Retinal Degeneration TherapiesR01EY017549 · NEI · UNIVERSITY OF PENNSYLVANIA · PI BELTRAN, WILLIAM A. · 2007 to 2024
$14.1M
SEARCH FOR NOVEL GENES AND MUTATIONS IN THE RP3 INTERVALR01EY013132 · NEI · UNIVERSITY OF PENNSYLVANIA · PI AGUIRRE, GUSTAVO DAVID · 2000 to 2007
$3.2M
NEI NIH HHS EY06855NEI NIH HHS R01 EY006855NEI NIH HHS R01 EY013132NEI NIH HHS R01 EY017549PHS HHS 13132PHS HHS 17549
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsApoptosisCell LineCell SurvivalDisease Models, AnimalDog DiseasesDogsGene Expression ProfilingGenetic TestingKidneyReproducibility of ResultsRetinal DegenerationSpecies Specificity

Identifiers

PMID22183353
PMCPMC3959790

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.