Evidence map›Paper›PMID 22183327›Full record

ReviewAdvances in experimental medicine and biology2012

Relieving bottlenecks in RNA drug discovery for retinal diseases.

Jack M Sullivan, Edwin H Yau, R Thomas Taggart, Mark C Butler, Tiffany A Kolniak

Abstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jack M SullivanDepartment of Ophthalmology, University at Buffalo, State University of New York (SUNY), SUNY Eye Institute, Buffalo, NY 14209, USA. jackmsullivanmdphd@yahoo.com
Edwin H Yau
R Thomas Taggart
Mark C Butler
Tiffany A Kolniak

Funding

A Ribozyme Rescue Strategy for Autosomal Dominant RPR01EY013433 · NEI · UPSTATE MEDICAL UNIVERSITY · PI SULLIVAN, JOHN M. · 2003 to 2019
$4.0M
UB VISION INFRASTRUCTURE CENTERR24EY016662 · NEI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI GONZALEZ-FERNANDEZ, FEDERICO · 2005 to 2009
$989k
A RIBOZYME RESCUE STRATEGY FOR DRY AGE-RELATED MACULAR DEGENERATIONI01BX000669 · VA · VA WESTERN NEW YORK HEALTHCARE SYSTEM · PI SULLIVAN, JOHN M. · 2009 to 2025
–
BLRD VA I01 BX000669NEI NIH HHS R01 EY013433NEI NIH HHS R01 EY13433NEI NIH HHS R24 EY016662NEI NIH HHS R24 EY16662
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

RNA InterferenceAnimalsDrug DiscoveryGenetic TherapyHumansRetinal DegenerationRNA, CatalyticThionucleotidesfomivirsenhammerhead ribozymeRNA, CatalyticThionucleotides

Identifiers

PMID22183327
PMCPMC5737907

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.