Trial reportEarly intervention in psychiatry2012
A randomized trial of family focused treatment for adolescents and young adults at risk for psychosis: study rationale, design and methods.
Trial report in Early intervention in psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01907282 (Prevention Trial of Family Focused Treatment in Youth at Risk for Psychosis), which is not on this map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevention Trial of Family Focused Treatment in Youth at Risk for Psychosis
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Interventions for prodromal stage of psychosis.The Cochrane database of systematic reviews · 2019Pooled it
- Psychoeducation (brief) for people with serious mental illness.The Cochrane database of systematic reviews · 2015Pooled it
- Psychoeducation for schizophrenia.The Cochrane database of systematic reviews · 2011Pooled it
- Race/ethnicity and socioeconomic status as predictors of outcome following family therapy in youth at clinical high risk for psychosis.Early intervention in psychiatry · 2024Trial
- Family communication and the efficacy of family focused therapy in individuals at clinical high risk for psychosis with comorbid anxiety.Early intervention in psychiatry · 2023Trial
- Family-focused therapy for individuals at clinical high risk for psychosis: treatment fidelity within a multisite randomized trial.Early intervention in psychiatry · 2016Trial
- Decreases in perceived maternal criticism predict improvement in subthreshold psychotic symptoms in a randomized trial of family-focused therapy for individuals at clinical high risk for psychosis.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2015Trial
- Effects of multidimensional treatment foster care on psychotic symptoms in girls.Journal of the American Academy of Child and Adolescent Psychiatry · 2014Trial
- A randomized trial of family focused therapy with populations at clinical high risk for psychosis: effects on interactional behavior.Journal of consulting and clinical psychology · 2014Trial
- Psychoeducation for individuals at clinical high risk for psychosis: A scoping review.Schizophrenia research · 2023Article
- The mood disorder spectrum vs. schizophrenia decision tree: EDIPHAS research into the childhood and adolescence of 205 patients.BMC psychiatry · 2022Article
- The Global Functioning: Social and Role Scales-Further Validation in a Large Sample of Adolescents and Young Adults at Clinical High Risk for Psychosis.Schizophrenia bulletin · 2019Article
- Flexibility and structure may enhance implementation of family-focused therapy in community mental health settings.Community mental health journal · 2014Article
- How should we intervene in psychosis risk syndromes?Shanghai archives of psychiatry · 2013Review
- Environmental Risk and Protective Factors and Their Influence on the Emergence of Psychosis.Adolescent psychiatry (Hilversum, Netherlands) · 2012Article
- Family-focused treatment for children and adolescents with bipolar disorder.The Israel journal of psychiatry and related sciences · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
aimThis article outlines the rationale for a family-focused psychoeducational intervention for individuals at risk for psychosis and explains the design of a randomized multisite trial to test its efficacy.
methodsAdolescents and young adults that meet criteria for a psychosis risk syndrome at eight participating North American Prodromal Longitudinal Study sites are randomly assigned to a 6-month, 18-session family-focused treatment for prodromal youth or a 3-session psychoeducational enhanced care control intervention and followed over 1 year.
resultsThe results will determine whether the use of a family intervention is able to significantly improve functional outcomes, decrease the severity of positive symptoms and possibly prevent the onset of full psychosis, compared with enhanced care alone. Levels of familial criticism at baseline are hypothesized to moderate responses to family intervention. Improvements in knowledge about symptoms, family communication and problem solving will be tested as mediators in the pathways between treatment assignment and clinical or psychosocial outcomes in high-risk youth.
conclusionsThe ongoing trial evaluates whether a non-invasive psychosocial approach can significantly enhance functional outcomes and prevent the ultra high risk patients from developing psychosis. The results will provide an important stepping stone in the movement of the field from refining early detection strategies to developing efficacious preventative treatments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.