Trial reportJournal of consulting and clinical psychology2012
Attendance and substance use outcomes for the Seeking Safety program: sometimes less is more.
Trial report in Journal of consulting and clinical psychology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Seeking safety intervention for comorbid post-traumatic stress and substance use disorder: A meta-analysis.Brain and behavior · 2023Pooled it
- A systematic review and meta-analysis of psychological interventions for comorbid post-traumatic stress disorder and substance use disorder.European journal of psychotraumatology · 2022Pooled it
- Psychological therapies for post-traumatic stress disorder and comorbid substance use disorder.The Cochrane database of systematic reviews · 2016Pooled it
- The Impact of Skill Utilization on Alcohol Use Outcomes Following Completion of a Brief Web-Based Alcohol Intervention.Substance use & misuse · 2026Trial
- Predictors of therapeutic alliance, treatment feedback, and clinical outcomes among African American women in treatment for co-occurring PTSD and SUD.Journal of substance abuse treatment · 2022Trial
- Substance use predictors of attendance among veterans in integrated PTSD and alcohol use disorder treatment.Journal of substance abuse treatment · 2021Trial
- Identifying attendance patterns in a smoking cessation treatment and their relationships with quit success.Drug and alcohol dependence · 2017Trial
- Pathways to change: Use trajectories following trauma-informed treatment of women with co-occurring post-traumatic stress disorder and substance use disorders.Drug and alcohol review · 2015Trial
- Who benefits from additional drug counseling among prescription opioid-dependent patients receiving buprenorphine-naloxone and standard medical management?Drug and alcohol dependence · 2014Trial
- Project Harmony 2.0: protocol for an updated and expanded individual patient data meta-analysis and virtual clinical trial of treatments for comorbid PTSD and substance use disorders.European journal of psychotraumatology · 2026Article
- A Framework for Estimating Posttreatment Moderation of Treatment-by-Dosage Effects in Individual-Patient Meta-Analysis: An Illustration Using Project Harmony.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- Kickin' it with the Gurlz: An evaluation of an HIV status-neutral intervention designed to address violence and trauma among transgender women of color in Detroit.Psychology of violence · 2025Article
- Behavioral activation for veterans with co-occurring alcohol use disorder and posttraumatic stress disorder: Basis and methodology for a pilot randomized controlled trial.Contemporary clinical trials · 2024Article
- Systems analysis and improvement approach to improve naloxone distribution within syringe service programs: study protocol of a randomized controlled trial.Implementation science : IS · 2023Article
- Decreases in psychiatric symptoms persist following exposure-based group therapy for sexual violence victimization among incarcerated women.Psychological services · 2022Article
- Design and methodology for an integrative data analysis of coping power: Direct and indirect effects on adolescent suicidality.Contemporary clinical trials · 2022Article
- Treatment of post-traumatic stress disorder and substance use disorder in adults with a history of adverse childhood experiences: A systematic review of psychological interventions.Drug and alcohol dependence reports · 2022Review
- Increasing knowledge about recovery-related life domains among pregnant and parenting women in comprehensive substance use disorder treatment: The Art of Addiction Recovery Program.Drug and alcohol dependence · 2022Article
- Preterm birth and its associated factors among reproductive aged women in sub-Saharan Africa: evidence from the recent demographic and health surveys of sub-Sharan African countries.BMC pregnancy and childbirth · 2021Article
- Seeing the forest for the trees: Predicting attendance in trials for co-occurring PTSD and substance use disorders with a machine learning approach.Journal of consulting and clinical psychology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveThis study uses data from the largest effectiveness trial to date on treatment of co-occurring posttraumatic stress and substance use disorders, using advances in statistical methodology for modeling treatment attendance and membership turnover in rolling groups.
methodWomen receiving outpatient substance abuse treatment (N = 353) were randomized to 12 sessions of Seeking Safety or a health education control condition. Assessments were completed at baseline and at 1 week, 3, 6, and 12 months posttreatment. Outcome measures were alcohol and cocaine use in the prior 30 days captured using the Addiction Severity Index. Latent class pattern mixture modeling (LCPMM) was used to estimate attendance patterns and to test for treatment effects within and across latent attendance patterns and group membership turnover.
resultsAcross LCPMM analyses for alcohol and cocaine use, similar treatment attendance patterns emerged: Completers never decreased below an 80% probability of attendance, droppers never exceeded a 41% probability of attendance, and titrators demonstrated a 50% to 80% probability of attendance. Among completers, there were significant decreases in alcohol use from baseline to 1-week posttreatment, followed by nonsignificant increases in alcohol during follow-up. No differences between treatment conditions were detected. Titrators in Seeking Safety had lower rates of alcohol use from 1-week through 12-month follow-up compared with control participants. Droppers had nonsignificant increases in alcohol during both study phases. Cocaine use findings were similar but did not reach significance levels.
conclusionsThe impact of client self-modulation of treatment dosage and group membership composition may influence behavioral treatment outcomes among this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.