ArticlePLoS neglected tropical diseases2011
Disability weight of Clonorchis sinensis infection: captured from community study and model simulation.
Article in PLoS neglected tropical diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Efficacy and safety of praziquantel, tribendimidine and mebendazole in patients with co-infection of Clonorchis sinensis and other helminths.PLoS neglected tropical diseases · 2014Trial
- Crafting an innovative one health-aligned machine learning framework for neglected tropical diseases elimination.Journal of advanced research · 2026Article
- Disability-adjusted life years of clonorchiasis in China: a high-resolution spatial analysis.Infectious diseases of poverty · 2025Article
- Epidemiology and risk factors of Clonorchis sinensis infection in the mountainous areas of Longsheng County, Guangxi: insights from automated machine learning.Parasitology research · 2025Article
- Schistosomiasis transmission in Zimbabwe: Modelling based on machine learning.Infectious Disease Modelling · 2024Article
- The disease burden and its distribution characteristics of clonorchiasis in Guangdong Province, Southern China.Parasites & vectors · 2024Article
- Clonorchiasis and opisthorchiasis: epidemiology, transmission, clinical features, morbidity, diagnosis, treatment, and control.Clinical microbiology reviews · 2024Review
- Modelling morbidity for neglected tropical diseases: the long and winding road from cumulative exposure to long-term pathology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Children education for sustainable control of liver fluke infections.Infectious diseases of poverty · 2022Article
- Effects of co-infection with Clonorchis sinensis on the sex hormones levels in male patients with chronic hepatitis B.Journal of clinical laboratory analysis · 2022Article
- Cost yield of different treatment strategies against Clonorchis sinensis infection.Infectious diseases of poverty · 2021Article
- Severe hepatobiliary morbidity is associated with Clonorchis sinensis infection: The evidence from a cross-sectional community study.PLoS neglected tropical diseases · 2021Article
- Clonorchiasis in Patients with Biliary and Pancreatic Diseases: Diagnosis and Risk Factors.BioMed research international · 2020Article
- Improving diagnostic performance of the Kato-Katz method for Clonorchis sinensis infection through multiple samples.Parasites & vectors · 2019Article
- Human liver flukes in China and ASEAN: Time to fight together.PLoS neglected tropical diseases · 2019Article
- Estimation of disability weight for paragonimiasis: a systematic analysis.Infectious diseases of poverty · 2018Review
- Modeling the Transmission Dynamics of Clonorchiasis in Foshan, China.Scientific reports · 2018Article
- Current status and perspectives of Clonorchis sinensis and clonorchiasis: epidemiology, pathogenesis, omics, prevention and control.Infectious diseases of poverty · 2016Review
- Characterization of the secreted cathepsin B cysteine proteases family of the carcinogenic liver fluke Clonorchis sinensis.Parasitology research · 2014Article
- Proteomic identification of potential Clonorchis sinensis excretory/secretory products capable of binding and activating human hepatic stellate cells.Parasitology research · 2014Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClonorchiasis is among the most neglected tropical diseases. It is caused by ingesting raw or undercooked fish or shrimp containing the larval of Clonorchis sinensis and mainly endemic in Southeast Asia including China, Korea and Vietnam. The global estimations for population at risk and infected are 601 million and 35 million, respectively. However, it is still not listed among the Global Burden of Disease (GBD) and no disability weight is available for it. Disability weight reflects the average degree of loss of life value due to certain chronic disease condition and ranges between 0 (complete health) and 1 (death). It is crucial parameter for calculating the morbidity part of any disease burden in terms of disability-adjusted life years (DALYs). METHODOLOGY/PRINCIPAL
findingsAccording to the probability and disability weight of single sequelae caused by C. sinensis infection, the overall disability weight could be captured through Monte Carlo simulation. The probability of single sequelae was gained from one community investigation, while the corresponding disability weight was searched from the literatures in evidence-based approach. The overall disability weights of the male and female were 0.101 and 0.050, respectively. The overall disability weights of the age group of 5-14, 15-29, 30-44, 45-59 and 60+ were 0.022, 0.052, 0.072, 0.094 and 0.118, respectively. There was some evidence showing that the disability weight and geometric mean of eggs per gram of feces (GMEPG) fitted a logarithmic equation. CONCLUSION/SIGNIFICANCE: The overall disability weights of C. sinensis infection are differential in different sex and age groups. The disability weight captured here may be referred for estimating the disease burden of C. sinensis infection.
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