ArticleJournal of magnetic resonance imaging : JMRI2012
Simultaneous field and R2 mapping to quantify liver iron content using autoregressive moving average modeling.
Article in Journal of magnetic resonance imaging : JMRI, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Liver iron susceptometry is different in patients with transfusion dependent thalassemia and sickle cell disease compared with hemochromatosis.Biochemistry and biophysics reports · 2025Article
- IDEAL-IQ measurement can distinguish dysplastic nodule from early hepatocellular carcinoma: a case-control study.Quantitative imaging in medicine and surgery · 2024Article
- Simulation of a virtual liver iron overload model and RNMR in biomedicine · 2023Article
- Quantitative MRI of diffuse liver diseases: techniques and tissue-mimicking phantoms.Magma (New York, N.Y.) · 2023Review
- Quantitative Susceptibility Mapping Using a Multispectral Autoregressive Moving Average Model to Assess Hepatic Iron Overload.Journal of magnetic resonance imaging : JMRI · 2021Article
- Autoregressive moving average modeling for hepatic iron quantification in the presence of fat.Journal of magnetic resonance imaging : JMRI · 2019Article
- Assessment of MR-based R2* and quantitative susceptibility mapping for the quantification of liver iron concentration in a mouse model at 7T.Magnetic resonance in medicine · 2018Article
- Fat spectral modeling on triglyceride composition quantification using chemical shift encoded magnetic resonance imaging.Magnetic resonance imaging · 2018Article
- Quantitative susceptibility mapping in combination with water-fat separation for simultaneous liver iron and fat fraction quantification.European radiology · 2018Article
- Fast quantitative parameter maps without fitting: Integration yields accurate mono-exponential signal decay rates.Magnetic resonance in medicine · 2018Article
- Quantification of liver iron concentration using the apparent susceptibility of hepatic vessels.Quantitative imaging in medicine and surgery · 2018Article
- Can multi-slice or navigator-gated R2* MRI replace single-slice breath-hold acquisition for hepatic iron quantification?Pediatric radiology · 2017Article
- Does fat suppression via chemically selective saturation affect R2*-MRI for transfusional iron overload assessment? A clinical evaluation at 1.5T and 3T.Magnetic resonance in medicine · 2016Article
- Algorithm for fast monoexponential fitting based on Auto-Regression on Linear Operations (ARLO) of data.Magnetic resonance in medicine · 2015Article
- Quantification of liver iron with MRI: state of the art and remaining challenges.Journal of magnetic resonance imaging : JMRI · 2014Review
- Quantitative proton MR techniques for measuring fat.NMR in biomedicine · 2013Review
- Magnetic susceptibility as a B0 field strength independent MRI biomarker of liver iron overload.Magnetic resonance in medicine · 2013Article
- Automated T(2) * measurements using supplementary field mapping to assess cardiac iron content.Journal of magnetic resonance imaging : JMRI · 2013Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo investigate the use of a complex multigradient echo (mGRE) acquisition and an autoregressive moving average (ARMA) model for simultaneous susceptibility and R 2 measurements for the assessment of liver iron content (LIC) in patients with iron overload. MATERIALS AND
methodsFifty magnetic resonance imaging (MRI) exams with magnitude and phase mGRE images were processed using the ARMA model, which provides fat-separated field maps, R 2 maps, and T(1) -W imaging. The LIC was calculated by measuring the susceptibility between the liver and the right transverse abdominal muscle from the field maps. The relationship between LIC derived from susceptibility measurements and LIC from R 2 measurements was determined using linear least-squares regression analysis.
resultsLIC measured from R 2 is highly correlated to the LIC with the susceptibility method (mg/g dry = 8.99 ± 0.15 × [mg Fe/mL of wet liver] -2.38 ± 0.29, R(2) = 0.94). The field inhomogeneity in the liver is correlated with R 2 (R(2) = 0.85).
conclusionBy using the ARMA model on complex mGRE images, both susceptibility and R 2-based LIC measurements can be made simultaneously. The susceptibility measurement can be used to help verify R 2 measurements in the assessment of iron overload.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.