Evidence map›Paper›PMID 22180269›Full record

ArticleCroatian medical journal2011

Haplotype frequencies of 17 Y-chromosomal short tandem repeat loci from the Cukurova region of Turkey.

Ayse Serin, Husniye Canan, Behnan Alper, Yasar Sertdemir

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Article in Croatian medical journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Y-chromosome variation in Basrah population.Journal of medicine and life · 2022
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Ayse SerinCukurova Universitesi, Tip Fakultesi, Adli Tip Anabilim Dali, Balcali, Adana, Turkey. ayserin@yahoo.com
Husniye Canan
Behnan Alper
Yasar Sertdemir

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the distribution of 17 Y-short tandem repeat (STR) loci in the population of the Cukurova region of Turkey.

methodsIn the period between 2009 and 2010, we investigated the distribution of 17 Y-STRs in a sample of 249 unrelated healthy men from the Cukurova region of Turkey. Genomic DNA was extracted with InstaGene matrix and Y-STRs were determined using the AmpFISTR Yfiler PCR amplification kit. Gene and haplotype diversity values were estimated using the Arlequin software. To compare our data to other populations, population pairwise genetic distances and associated probability values were calculated using the Y Chromosome Haplotype Reference Database Web site software.

resultsAt 17 Y-STR loci we detected 148 alleles. The lowest gene diversity in this region was 0.51 for DYS391 and the highest 0.95 for DYS385a/b. Haplotype diversity was 0.9997±0.0004. We compared our data with haplotype data of other Turkish populations and no significant differences were found, except with Ankara population (Φst=0.025, P=0.018). Comparisons were also made with the neighboring populations using analysis of molecular variance of the Y-STR loci genetic structure and our population was nearest to Lenkoran-Azerbaijani (Φst=0.012, P=0.068) and Iranian Ahvaz population (Φst=0.007, P=0.173), followed by Greek (Φst=0.025, P=0.000) and Russian (Φst=0.048, P=0.000) population. Other countries like Portugal, Spain, Italy, Egypt, Israel (Palestinian Authority Area), and Taiwan showed a high genetic distance from our population.

conclusionOur study showed that Y-STR polymorphisms were a powerful discrimination tool for routine forensic applications and could be used in genealogical investigations.

Indexed as

AllelesChromosomes, Human, YGene FrequencyGenetic VariationHaplotypesHumansMaleMicrosatellite RepeatsPolymorphism, GeneticTurkey

Identifiers

PMID22180269
PMCPMC3243320

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