Evidence map›Paper›PMID 22179294›Full record

ReviewJournal of the Royal Society of Medicine2011

The answer is 17 years, what is the question: understanding time lags in translational research.

Zoë Slote Morris, Steven Wooding, Jonathan Grant

8 registry-linked trialsAbstract readReview
In one paragraph

Review in Journal of the Royal Society of Medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 1,257 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,257citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05133479 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

Translating Research Into School-based Practice Via Small-group, Language-focused Comprehension Intervention

TypeinterventionalSponsorMGH Institute of Health ProfessionsRan2021 to 2026Enrolled241ConditionsLanguage Disorders in ChildrenArmsLet's Know! small-group or TierL 2 Intervention
NCT05294614 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Implementation of a Psychological Online Intervention for Low to Moderate Depression in Primary Health Care: a Study Protocol

TypeinterventionalSponsorUniversitat Jaume IRan2022 to 2023Enrolled420ConditionsDepressive Disorder, Depressive Symptoms, DepressionArms"Sonreír es diveritdo" - Smiling is fun
NCT05466656 naunknown statusnot on this mapstarted 2021, after this paper: background citation

SUMAMOS EXCELENCIA Project: Assessment of Implementation of Best Practices in a National Health System (Second Edition)

TypeinterventionalSponsorTeresa Moreno CasbasRan2021 to 2024Enrolled115ConditionsPain, Incontinence, Urinary, Obesity, Childhood, BreastfeedingArmsContinuous quality improvement cycle model
NCT06358339 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Tailored Evidence-based Enhancements in Mental Health-Gamified and Individualized Follow-Up Treatment for Suicide (TEEM-GIFTS) : Implementing a Gamified mHealth Intervention to Reduce Post-Discharge Suicide Risk in Patients With Mental Disorders Using Multiphase Optimization Strategy (MOST)

TypeinterventionalSponsorShenzhen Kangning HospitalRan2025 to 2027Enrolled640ConditionsSuicideArmsTEEM
NCT06366100 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Dissemination, Acceptability and Adaptation Study of Two Transdiagnostic Psychological Interventions Based on Emotional Regulation (ER) for the Treatment of Alcohol Addiction: Dialectical Behavioral Therapy(DBT) and Unified Protocol (UP)

TypeinterventionalSponsorUniversidad de ZaragozaRan2024 to 2025Enrolled160ConditionsImplementation ScienceArmsDialectical Behavior Therapy for Substance Use Disorder (DBT-SUD), Unified Protocol (UP)
NCT06522529 naunknown statusnot on this mapstarted 2024, after this paper: background citation

SUMAMOS EXCELENCIA Project: Assessment of Implementation of Best Practices in a National Health System (Thrid Edition)

TypeinterventionalSponsorInstituto de Salud Carlos IIIRan2024 to 2026Enrolled400ConditionsPain, Obesity, Childhood, Breast Feeding, Incontinence, UrinaryArmsMultifaceted implementation strategy
NCT06691880 nacompletednot on this mapstarted 2020, after this paper: background citation

Translating SMARTS 2: the Integration of Video Gaming Technology Into Traditional Rehabilitation

TypeinterventionalSponsorJohns Hopkins UniversityRan2020 to 2025Enrolled58ConditionsSubacute Stroke, Acute StrokeArmsMindPod Dolphin VGT, Bimanual Arm Trainer VGT
NCT07166653 narecruitingnot on this mapstarted 2025, after this paper: background citation

Nordic Digital Health Education as an Implementation Tool for Hospital-at-home - Protocol for a Multicenter Randomized Controlled Trial

TypeinterventionalSponsorNordsjaellands HospitalRan2025 to 2026Enrolled14ConditionsHospitalArmsHaH education
3 · Its place in the literature

Who cites it

1,257 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
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  13. Improving science will require more than just training.Clinical psychological science : a journal of the Association for Psychological Science · 2026
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  15. Review
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1,197 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Zoë Slote MorrisInstitute of Public Health, University of Cambridge, Cambridge CB2 0SR, UK.
Steven Wooding
Jonathan Grant

Funding

Department of Health
6 · The paper itself

Abstract

This study aimed to review the literature describing and quantifying time lags in the health research translation process. Papers were included in the review if they quantified time lags in the development of health interventions. The study identified 23 papers. Few were comparable as different studies use different measures, of different things, at different time points. We concluded that the current state of knowledge of time lags is of limited use to those responsible for R&D and knowledge transfer who face difficulties in knowing what they should or can do to reduce time lags. This effectively 'blindfolds' investment decisions and risks wasting effort. The study concludes that understanding lags first requires agreeing models, definitions and measures, which can be applied in practice. A second task would be to develop a process by which to gather these data.

Indexed as

ResearchSystems AnalysisTranslational Research, BiomedicalHumansKnowledge BasesKnowledge ManagementModels, TheoreticalResearch DesignTime Factors

Identifiers

PMID22179294
PMCPMC3241518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.