ArticleDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete2012
[Human papillomavirus (HPV) and head and neck cancer].
Article in Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Human Papillomavirus (HPV) Prevalence in Nasal and Antrochoanal Polyps and Association with Clinical Data.PloS one · 2015Article
- C2-ceramide induces cell death and protective autophagy in head and neck squamous cell carcinoma cells.International journal of molecular sciences · 2014Article
- 30th german cancer congress, 22nd-25th february 2012, berlin.Ecancermedicalscience · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Squamous cell carcinomas of the head and neck belong to the most common cancers worldwide. Although they are in general on the decline, rising incidence rates have been reported for certain specific sites. In developed countries the impact of classical risk factors like tobacco and alcohol seems to decline, while the association with oncogenic papillomavirus infections, in particular in cancers of the oropharynx, is increasing markedly. The accumulation of genetic and epigenetic changes due to toxin exposure leads to inactivation of tumor suppressors or activation of proto-oncogenes, resulting in genetic instability and malignant transformation in non-papillomavirus-related cancer. Papillomavirus-related cancers infrequently contain genetic alterations and are caused by deregulation of the cell cycle, senescence and apoptosis induced by viral oncoproteins. Detection of oncogenic papillomavirus infections may be basis for further classification of head and neck squamous cell carcinoma and could be a key in differential treatment modalities for subsets of head and neck cancer in the near future.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.