Evidence map›Paper›PMID 22179017›Full record

ReviewArchives of biochemistry and biophysics2012

Vitamin D safety and requirements.

Francisco J A de Paula, Clifford J Rosen

Abstract readReview
In one paragraph

Review in Archives of biochemistry and biophysics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Vitamin D-is the sun enough for us?Nutrition & metabolism · 2025
    Review
  2. Vitamin D affects antiphospholipid syndrome by regulating T cells (Review).International journal of molecular medicine · 2025
    Review
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Diabetes and bone.Archives of endocrinology and metabolism · 2022
    Review
  9. Bone, fat, and muscle interactions in health and disease.Archives of endocrinology and metabolism · 2022
    Review
  10. Vitamin D Level Testing in an Urban Midwest Clinic: To Test or Not to Test?Journal of patient-centered research and reviews · 2022
    Article
  11. Article
  12. Hashtag bone: detrimental effects on bone contrast with metabolic benefits one and five years after Roux-en-Y gastric bypass.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021
    Article
  13. Article
  14. Vitamin D: more does not mean better.Archives of endocrinology and metabolism · 2020
    Article
  15. What Value is there in Assessing Postmenopausal Women for Vitamin D Deficiency?Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2017
    Article
  16. Review
  17. Does the Access to Sun Exposure Ensure Adequate Levels of 25-Hydroxyvitamin D?Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2017
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Francisco J A de PaulaDepartment of Internal Medicine, School of Medicine of Ribeirão Preto, University of São Paulo, Av. Bandeirantes 3900, Ribeirão Preto, 14049-900 SP, Brazil. fjpaula@fmrp.usp.br
Clifford J Rosen

Funding

Seasonal Bone Loss in MiceR21AR055633 · NIAMS · JACKSON LABORATORY · PI ROSEN, CLIFFORD JAMES · 2007 to 2008
$406k
A link between parity, trunk muscle function, and degenerative spondylolisthesisR21AR056404 · NIAMS · MICHIGAN STATE UNIVERSITY · PI CHOLEWICKI, JACEK, MYSLIWIEC, LAWRENCE W. · 2010 to 2011
$360k
NIAMS NIH HHS AR 56404NIAMS NIH HHS R21 AR055633
6 · The paper itself

Abstract

Vitamin D an ancient secosteroid is essential for mineral homeostasis, bone remodeling, immune modulation, and energy metabolism. Recently, debates have emerged about the daily vitamin D requirements for healthy and elderly adults, the safety and efficacy of long term supplementation and the role of vitamin D deficiency in several chronic disease states. Since this molecule acts as both a vitamin and a hormone, it should not be surprising that the effects of supplementation are multi-faceted and complex. Yet despite significant progress in the last decade, our understanding of vitamin D physiology and the clinical relevance of low circulating levels of this vitamin remains incomplete. The present review provides the reader with a comprehensive and up-to-date understanding of vitamin D requirements and safety. It also raises some provocative research questions.

Indexed as

AnimalsDrug-Related Side Effects and Adverse ReactionsHumansSeasonsSkin PigmentationSunlightVitamin DVitamin D DeficiencyVitamin D

Identifiers

PMID22179017
PMCPMC3311750

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.