Evidence map›Paper›PMID 22178089›Full record

ReviewMolecular and cellular endocrinology2012

Environmental signaling and reproduction: a comparative biological and chemical perspective.

John A McLachlan, Syreeta L Tilghman, Matthew E Burow, Melyssa R Bratton

Abstract readReview
In one paragraph

Review in Molecular and cellular endocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Pathway for biodegrading coumarin by a newly isolated Pseudomonas sp. USTB-Z.World journal of microbiology & biotechnology · 2021
    Article
  2. Review
  3. Endocrine Disruptors in Domestic Animal Reproduction: A Clinical Issue?Reproduction in domestic animals = Zuchthygiene · 2015
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John A McLachlanEnvironmental Signaling Laboratory, Tulane University, 1430 Tulane Ave., New Orleans, LA 70122, USA.
Syreeta L Tilghman
Matthew E Burow
Melyssa R Bratton

Funding

Xavier's RCMI Cancer Research ProgramG12MD007595 · NIMHD · XAVIER UNIVERSITY OF LOUISIANA · PI D'AMOUR, GENE, WANG, GUANGDI · 2012 to 2018
$15.7M
XAVIER'S RCMI CANCER RESEARCH PROGRAMG12RR026260 · NCRR · XAVIER UNIVERSITY OF LOUISIANA · PI WIESE, THOMAS E · 2009 to 2011
$7.0M
NCRR NIH HHS G12 RR026260NIMHD NIH HHS G12 MD007595
6 · The paper itself

Abstract

Reproduction is a critical element of life. Self-propagation in all living organisms ranging from bacteria to humans involves numerous common strategies. Underlying all reproductive strategies is the essential need for signaling molecules to initiate and maintain the process. In this paper we use comparative biological and chemical approaches to explore the origins and distribution of estrogen signaling as a pathway common to many life forms. In the process we illuminate the mechanisms whereby environmental agents alter reproduction and development. These mechanisms involve altered signaling pathways within cells and shifts in the targets of the signaling pathways to include regulators of gene transcription normally associated with other pathways. We also stress the role of signal cross talk in mediating hormone action.

Indexed as

ReproductionAnimalsEndocrine DisruptorsEnvironmental PollutantsEstrogensHumansSignal TransductionEndocrine DisruptorsEnvironmental PollutantsEstrogens

Identifiers

PMID22178089
PMCPMC3641892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.