ArticleDrug and alcohol dependence2012
Two-part random effects growth modeling to identify risks associated with alcohol and cannabis initiation, initial average use and changes in drug consumption in a sample of adult, male twins.
Article in Drug and alcohol dependence, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium.Translational psychiatry · 2016Pooled it
- Can cannabis use be prevented by targeting personality risk in schools? Twenty-four-month outcome of the adventure trial on cannabis use: a cluster-randomized controlled trial.Addiction (Abingdon, England) · 2015Trial
- Dopamine modulates risk-taking as a function of baseline sensation-seeking trait.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Trial
- The genetic aetiology of cannabis use: from twin models to genome-wide association studies and beyond.Translational psychiatry · 2022Review
- Impulsivities and addictions: a multidimensional integrative framework informing assessment and interventions for substance use disorders.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Review
- The Genetic and Environmental Association Between Parental Monitoring and Risk of Cannabis, Stimulants, and Cocaine Initiation in a Sample of Male Twins: Does Parenting Matter?Twin research and human genetics : the official journal of the International Society for Twin Studies · 2016Article
- Genetic and Environmental Factors Associated with Cannabis Involvement.Current addiction reports · 2016Article
- Impulsivity in abstinent alcohol and polydrug dependence: a multidimensional approach.Psychopharmacology · 2016Article
- Clinical and Social/Environmental Characteristics in a Community Sample of Children With and Without Family Histories of Substance Use Disorder in the San Antonio Area: A Descriptive Study.Journal of child & adolescent substance abuse · 2016Article
- Oral operant ethanol self-administration in the absence of explicit cues, food restriction, water restriction and ethanol fading in C57BL/6J mice.Psychopharmacology · 2015Article
- The temporal "pulse" of drinking: Tracking 5 years of binge drinking in emerging adults.Journal of abnormal psychology · 2015Article
- Marijuana: current concepts(†).Frontiers in public health · 2013Review
- The Brisbane Longitudinal Twin Study: Pathways to Cannabis Use, Abuse, and Dependence project-current status, preliminary results, and future directions.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2013Article
- The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses.Behavior genetics · 2012Article
- The detrimental effects of emotional process dysregulation on decision-making in substance dependence.Frontiers in integrative neuroscience · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
aimsOur aim was to profile alcohol and cannabis initiation and to characterize the effects of developmental and environmental risk factors on changes in average drug use over time.
designWe fitted a two-part random effects growth model to identify developmental and environmental risks associated with alcohol and cannabis initiation, initial average use and changes in average use.
participants1796 males aged 24-63 from the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders. MEASUREMENTS: Data from three interview waves included self-report measures of average alcohol and cannabis use between ages 15 and 24, genetic risk of problem drug use, childhood environmental risks, personality, psychiatric symptoms, as well as personal, family and social risk factors.
findingsAverage alcohol and cannabis use were correlated at all ages. Genetic risk of drug use based on family history, higher sensation seeking, and peer group deviance predicted both alcohol and cannabis initiation. Higher drug availability predicted cannabis initiation while less parental monitoring and drug availability were the best predictors of how much cannabis individuals consumed over time.
conclusionThe liability to initiate alcohol and cannabis, average drug use as well as changes in drug use during teenage years and young adulthood is associated with known risk factors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.