ReviewTrends in neurosciences2012
Sensing sound: molecules that orchestrate mechanotransduction by hair cells.
Review in Trends in neurosciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed.
- Review
- CASZ1 regulates the maturation of outer hair cells and is required for hearing in mice.iScience · 2026Article
- Deafness causing neuroplastin missense variants fail to promote plasma membrane CaThe Journal of biological chemistry · 2024Article
- Involvement of Dmp1 in the Precise Regulation of Hair Bundle Formation in the Developing Cochlea.Biology · 2023Article
- Review
- Vestibular Deficits in Deafness: Clinical Presentation, Animal Modeling, and Treatment Solutions.Frontiers in neurology · 2022Review
- Axonemal Dynein DNAH5 is Required for Sound Sensation in Drosophila Larvae.Neuroscience bulletin · 2021Article
- The Kinocilia of Cochlear Hair Cells: Structures, Functions, and Diseases.Frontiers in cell and developmental biology · 2021Review
- Deletion ofFrontiers in cell and developmental biology · 2021Article
- Function and Dysfunction of TMC Channels in Inner Ear Hair Cells.Cold Spring Harbor perspectives in medicine · 2019Review
- Genomic architecture of Shh-dependent cochlear morphogenesis.Development (Cambridge, England) · 2019Article
- Transient Receptor Potential Cation Channel Subfamily Vanilloid 4 and 3 in the Inner Ear Protect Hearing in Mice.Frontiers in molecular neuroscience · 2019Article
- TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells.Neuron · 2018Article
- The stable actin core of mechanosensory stereocilia features continuous turnover of actin cross-linkers.Molecular biology of the cell · 2018Article
- [Molecular Understanding of Hearing - How Does This Matter to the Hearing Impaired?]Laryngo- rhino- otologie · 2018Review
- Mechanically Gated Ion Channels in Mammalian Hair Cells.Frontiers in cellular neuroscience · 2018Review
- Role of Calcium-Sensing Receptor in Mechanotransducer-Channel-Mediated CaFrontiers in physiology · 2018Article
- ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development.Developmental cell · 2017Article
- Myosin 7 and its adaptors link cadherins to actin.Nature communications · 2017Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Animals use acoustic signals to communicate and to obtain information about their environment. The processing of acoustic signals is initiated at auditory sense organs, where mechanosensory hair cells convert sound-induced vibrations into electrical signals. Although the biophysical principles underlying the mechanotransduction process in hair cells have been characterized in much detail over the past 30 years, the molecular building-blocks of the mechanotransduction machinery have proved to be difficult to determine. We review here recent studies that have both identified some of these molecules and established the mechanisms by which they regulate the activity of the still-elusive mechanotransduction channel.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.