ArticleEnvironmental health : a global access science source2011
Relation between dietary cadmium intake and biomarkers of cadmium exposure in premenopausal women accounting for body iron stores.
Article in Environmental health : a global access science source, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Toxic Metals and Chronic Kidney Disease: a Systematic Review of Recent Literature.Current environmental health reports · 2018Pooled it
- Cadmium Exposure and Risk of Any Fracture: A PRISMA-Compliant Systematic Review and Meta-Analysis.Medicine · 2016Pooled it
- Pooled it
- Serum 25‑hydroxyvitamin D and dietary calcium intake interact in relation to blood cadmium in pregnant women: evidence from the NHANES survey.BMC pregnancy and childbirth · 2025Article
- Relationship between blood cadmium levels and bone mineral density in adults: a cross-sectional study.Frontiers in endocrinology · 2024Article
- Urine cadmium and acute myocardial infarction among never smokers in the Danish Diet, Cancer and Health cohort.Environment international · 2021Article
- Information Retrieval Using Machine Learning for Biomarker Curation in the Exposome-Explorer.Frontiers in research metrics and analytics · 2021Article
- Comparison of Methodologies to Estimate Dietary Cadmium Intake in an Italian Population.International journal of environmental research and public health · 2020Article
- The association between cumulative cadmium intake and osteoporosis and risk of fracture in a Chinese population.Journal of exposure science & environmental epidemiology · 2019Article
- Urine and toenail cadmium levels in pregnant women: A reliability study.Environment international · 2018Article
- Dietary Cadmium Intake and Its Effects on Kidneys.Toxics · 2018Review
- Factors affecting the variability in the observed levels of cadmium in blood and urine among former and current smokers aged 20-64 and ≥ 65years.Environmental science and pollution research international · 2017Article
- Factors affecting the variability in the observed levels of urinary cadmium among children and nonsmoker adolescents.Environmental science and pollution research international · 2017Article
- Dietary predictors of urinary cadmium among pregnant women and children.The Science of the total environment · 2017Article
- Is Urinary Cadmium a Biomarker of Long-term Exposure in Humans? A Review.Current environmental health reports · 2016Review
- Cadmium levels in a representative sample of the Spanish adult population: The BIOAMBIENT.ES project.Journal of exposure science & environmental epidemiology · 2016Article
- Article
- Physiologically-based toxicokinetic model for cadmium using Markov-chain Monte Carlo analysis of concentrations in blood, urine, and kidney cortex from living kidney donors.Toxicological sciences : an official journal of the Society of Toxicology · 2014Article
- Article
- Determinants and within-person variability of urinary cadmium concentrations among women in northern California.Environmental health perspectives · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCadmium is a widespread environmental pollutant with adverse effects on kidneys and bone, but with insufficiently elucidated public health consequences such as risk of end-stage renal diseases, fractures and cancer. Urinary cadmium is considered a valid biomarker of lifetime kidney accumulation from overall cadmium exposure and thus used in the assessment of cadmium-induced health effects. We aimed to assess the relationship between dietary cadmium intake assessed by analyses of duplicate food portions and cadmium concentrations in urine and blood, taking the toxicokinetics of cadmium into consideration.
methodsIn a sample of 57 non-smoking Swedish women aged 20-50 years, we assessed Pearson's correlation coefficients between: 1) Dietary intake of cadmium assessed by analyses of cadmium in duplicate food portions collected during four consecutive days and cadmium concentrations in urine, 2) Partial correlations between the duplicate food portions and urinary and blood cadmium concentrations, respectively, and 3) Model-predicted urinary cadmium concentration predicted from the dietary intake using a one-compartment toxicokinetic model (with individual data on age, weight and gastrointestinal cadmium absorption) and urinary cadmium concentration.
resultsThe mean concentration of cadmium in urine was 0.18 (+/- s.d.0.12) μg/g creatinine and the model-predicted urinary cadmium concentration was 0.19 (+/- s.d.0.15) μg/g creatinine. The partial Pearson correlations between analyzed dietary cadmium intake and urinary cadmium or blood concentrations were r = 0.43 and 0.42, respectively. The correlation between diet and urinary cadmium increased to r = 0.54 when using a one-compartment model with individual gastrointestinal cadmium absorption coefficients based on the women's iron status.
conclusionsOur results indicate that measured dietary cadmium intake can reasonably well predict biomarkers of both long-term kidney accumulation (urine) and short-term exposure (blood). The predictions are improved when taking data on the iron status into account.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.