ArticleBJU international2012
Association of overactive bladder and C-reactive protein levels. Results from the Boston Area Community Health (BACH) Survey.
Article in BJU international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Biomarkers Implicated in Lower Urinary Tract Symptoms: Systematic Review and Pathway Analyses.The Journal of urology · 2019Pooled it
- Therapeutic potential of MitoQ, a mitochondria-targeted antioxidant, in age-related physiological dysfunction.GeroScience · 2026Review
- Association between systemic immune-inflammation index and urinary incontinence: Evidence from the National Health and Nutrition Examination Survey.The Journal of international medical research · 2026Article
- Chop Deficiency Exacerbates Cyclophosphamide-Induced Overactive Bladder via Impaired Macrophage Apoptosis.Current medical science · 2025Article
- Role of Combined Use of Adiponectin and hsCRP in Cardiovascular Risk in Pediatric Neurogenic Bladder.Children (Basel, Switzerland) · 2025Article
- Red blood cell distribution width to albumin ratio and urinary incontinence subtypes in NHANES 2007-2018.Scientific reports · 2025Article
- Association between novel inflammatory markers and overactive bladder: a cross-sectional study of NHANES 2009 to 2018.BMC urology · 2025Article
- Sleep duration and overactive bladder syndrome in US adults: a propensity score matching cohort study using NHANES 2005-2018.Frontiers in neurology · 2025Article
- Association of neutrophil to high-density lipoprotein cholesterol ratio with overactive bladder: a population-based study.Frontiers in endocrinology · 2025Article
- Characterizing the spectrum of bladder health and lower urinary tract symptoms among men: Results from the CARDIA study.Neurourology and urodynamics · 2024Article
- Composite dietary antioxidant index in relation to urge urinary incontinence in US men.Frontiers in nutrition · 2024Article
- Article
- Associations between the dietary inflammatory index and urinary incontinence among women younger than 65 years.Scientific reports · 2021Article
- Urinary Incontinence in Chronic Obstructive Pulmonary Disease: A Common Co-morbidity or a Typical Adverse Effect?Drugs & aging · 2019Article
- Inflammatory mediators in the development and progression of benign prostatic hyperplasia.Nature reviews. Urology · 2016Review
- Article
- Article
- Overactive bladder in elderly men: epidemiology, evaluation, clinical effects, and management.Current urology reports · 2013Review
- Article
- Association of insulin resistance with overactive bladder in female patients.International neurourology journal · 2012Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objective• To investigate the association between overactive bladder (OAB) and C-reactive protein (CRP) in a population-based sample of men and women. SUBJECTS AND
methods• Epidemiological survey of urological symptoms among men and women aged 30-79 years. A multi-stage stratified cluster design was used to randomly sample 5503 adults from the city of Boston. Analyses were conducted on 1898 men and 1854 women with available CRP levels. • The International Continence Society defines OAB as 'Urgency with or without urge incontinence, usually with frequency and nocturia.' OAB was defined as: (1) urgency, (2) urgency with frequency, and (3) urgency with frequency and nocturia. • Odds ratios (OR) and 95% confidence intervals (95% CI) of the CRP and OAB association were estimated using logistic regression.
results• Prevalence of OAB increased with CRP levels in both men and women. • In men, adjusted ORs (95% CI) per log(10) (CRP) levels were 1.90 (1.26-2.86) with OAB defined as urgency, 1.65 (1.06-2.58) with OAB defined as urgency and frequency, and 1.92 (1.13-3.28) with OAB defined as urgency, frequency and nocturia. • The association was more modest in women with ORs (95% CI) of 1.53 (1.07-2.18) for OAB as defined urgency, 1.51 (1.02-2.23) for OAB defined as urgency and frequency, and 1.34 (0.85-2.12) for OAB defined as urgency, frequency and nocturia.
conclusions• Results show a consistent association of increasing CRP levels and OAB among both men and women. • These results support our hypothesis for the role of inflammation in the development of OAB and a possible role for anti-inflammatory agents in its treatment.
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Registered trials
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