Trial reportScandinavian journal of primary health care2012
Drug treatment in the elderly: an intervention in primary care to enhance prescription quality and quality of life.
Trial report in Scandinavian journal of primary health care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 14 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 14 syntheses or guidelines pooled it.
- Evaluating the role of clinical decision support systems in medication safety for older people: a systematic review.Age and ageing · 2025Pooled it
- Interventions to Address Potentially Inappropriate Prescribing for Older Primary Care Patients: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- A systematic review of outcomes reported in studies to optimise the medication use of patients at hospital discharge.BMC health services research · 2025Pooled it
- Interventions to improve the appropriate use of polypharmacy for older people.The Cochrane database of systematic reviews · 2023Pooled it
- The effects of clinical decision support system for prescribing medication on patient outcomes and physician practice performance: a systematic review and meta-analysis.BMC medical informatics and decision making · 2021Pooled it
- Deprescribing for Community-Dwelling Older Adults: a Systematic Review and Meta-analysis.Journal of general internal medicine · 2020Pooled it
- Interventions to Reduce Adverse Drug Event-Related Outcomes in Older Adults: A Systematic Review and Meta-analysis.Drugs & aging · 2020Pooled it
- Patient-mediated interventions to improve professional practice.The Cochrane database of systematic reviews · 2018Pooled it
- Interventions to improve the appropriate use of polypharmacy for older people.The Cochrane database of systematic reviews · 2018Pooled it
- Effectiveness of medication review: a systematic review and meta-analysis of randomized controlled trials.BMC family practice · 2017Pooled it
- [Effectiveness of interventions for improving drug prescribing in Primary Health Care].Atencion primaria · 2017Pooled it
- Impact of strategies to reduce polypharmacy on clinically relevant endpoints: a systematic review and meta-analysis.British journal of clinical pharmacology · 2016Pooled it
- A systematic review of instruments for measuring outcomes in economic evaluation within aged care.Health and quality of life outcomes · 2015Pooled it
- Patient participation in medication reviews is desirable but not evidence-based: a systematic literature review.British journal of clinical pharmacology · 2014Pooled it
- Trial
- A randomized controlled trial comparing two ways of providing evidence-based drug information to GPs.Scandinavian journal of primary health care · 2013Trial
- Measuring Quality of Life in Deprescribing Trials: A Scoping Review.Drugs & aging · 2024Article
- A framework for elderly participation in Primary Health Care in Tabriz Health complexes.BMC geriatrics · 2023Article
- One-Year Evaluation of a Targeted Medication Therapy Management Intervention for Older Adults.Journal of managed care & specialty pharmacy · 2020Observational
- Impact of training and structured medication review on medication appropriateness and patient-related outcomes in nursing homes: results from the interventional study InTherAKT.BMC geriatrics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of the study was to assess the effect on prescription quality and quality of life after intervention with prescription reviews and promotion of patient participation in primary care.
designA randomized controlled study with three groups: (A) controls, (B) prescription review sent to physician, and (C) as in B and with a current comprehensive medication record sent to the patient.
settingThe municipality of Örebro, Sweden (130 000 inhabitants).
interventionThe study focused on the easiest possible intervention to increase prescription quality and thereby increase quality of life. The intervention should be cost-efficient, focus on colleague-to-colleague advice, and be possible to perform in the primary health care centre without additional resources such as a pharmacist. SUBJECTS: 150 patients recently discharged from hospital. Inclusion criteria were: ≥ 75 years, ≥ five drugs and living in ordinary homes.
main outcome measuresQuality of life (EQ-5D index, EQ VAS) and quality of prescriptions.
resultsExtreme polypharmacy was common and persistent in all three groups and this was accompanied by an unchanged frequency of drug-risk indicators. There was a low EQ-5D index and EQ VAS in all three groups throughout the study. No statistically significant differences were found anywhere between the groups.
conclusionThe intervention seems to have had no effect on quality of prescriptions or quality of life. This underlines the major challenge of finding new strategies for improving prescription quality to improve patient outcome measures such as quality of life and reduce the known risks of polypharmacy for the elderly.
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