Evidence map›Paper›PMID 22175023›Full record

ReviewJournal of pregnancy2012

Preeclampsia, hypoxia, thrombosis, and inflammation.

Amir A Shamshirsaz, Michael Paidas, Graciela Krikun

Abstract readReview
In one paragraph

Review in Journal of pregnancy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Observational
  14. Article
  15. Observational
  16. Review
  17. Article
  18. Article
  19. Article
  20. Placental pathology varies in hypertensive conditions of pregnancy.Virchows Archiv : an international journal of pathology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amir A ShamshirsazDepartment of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, Yale University, New Haven, CT 06520, USA.
Michael Paidas
Graciela Krikun

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reductions in uteroplacental flow initiate a cascade of molecular effects leading to hypoxia, thrombosis, inflammation, and endothelial cell dysfunction resulting in untoward pregnancy outcomes. In this review, we detail these effects and their relationship to preeclampsia (PE) and intrauterine growth restriction (IUGR).

Indexed as

Angiogenic ProteinsBiomarkersBlood Coagulation FactorsCatechol O-MethyltransferaseComplement System ProteinsEndometriumFemaleFetal Growth RetardationHumansHypoxiaInflammationMaternal-Fetal ExchangePlacenta DiseasesPre-EclampsiaPregnancyThrombosisAngiogenic ProteinsBiomarkersBlood Coagulation FactorsCatechol O-MethyltransferaseComplement System Proteins

Identifiers

PMID22175023
PMCPMC3235807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.