ArticleJournal of transplantation2011
Striated muscle as implantation site for transplanted pancreatic islets.
Article in Journal of transplantation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Co-transplantation of pancreatic islets with adipose-derived mesenchymal stem cells in vascularized kidney ECM scaffolds to restore type 1 diabetes mellitus.Bioactive materials · 2026Article
- Suitability of denervated muscle flaps as recipient sites for pancreatic islet cell transplantation.Archives of plastic surgery · 2021Article
- Considerations for an Alternative Site of Islet Cell Transplantation.Journal of diabetes science and technology · 2020Review
- Characterization of neural crest-derived stem cells isolated from human bone marrow for improvement of transplanted islet function.Upsala journal of medical sciences · 2019Article
- c-Jun N-terminal kinase 1 defective CD4+CD25+FoxP3+ cells prolong islet allograft survival in diabetic mice.Scientific reports · 2018Article
- Pig-to-Primate Islet Xenotransplantation: Past, Present, and Future.Cell transplantation · 2017Review
- Treatment of diabetes with encapsulated pig islets: an update on current developments.Journal of Zhejiang University. Science. B · 2015Review
- Bioengineered stem cells as an alternative for islet cell transplantation.World journal of transplantation · 2015Review
- Transplantation of pancreatic islets to adrenal gland is promoted by agonists of growth-hormone-releasing hormone.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Macro- or microencapsulation of pig islets to cure type 1 diabetes.World journal of gastroenterology · 2012Review
- Enhancement of Subcutaneous Islet Transplant Performance by Collagen 1 Gel.Cell transplantationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Islet transplantation is an attractive treatment for selected patients with brittle type 1 diabetes. In the clinical setting, intraportal transplantation predominates. However, due to extensive early islet cell death, the quantity of islets needed to restore glucose homeostasis requires in general a minimum of two donors. Moreover, the deterioration of islet function over time results in few insulin-independent patients after five-year followup. Specific obstacles to the success of islet transplantation include site-specific concerns for the liver such as the instant blood mediated inflammatory reaction, islet lipotoxicity, low oxygen tension, and poor revascularization, impediments that have led to the developing interest for alternative implantation sites over recent years. Within preclinical settings, several alternative sites have now been investigated and proven favorable in various aspects. Muscle is considered a very promising site and has physiologically properties and technical advantages that could make it optimal for islet transplantation.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.