Evidence map›Paper›PMID 22174975›Full record

ReviewToxins2011

Understanding ricin from a defensive viewpoint.

Gareth D Griffiths

Abstract readReview
In one paragraph

Review in Toxins, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Ricin poisoning after oral ingestion of castor beans: A case report and literature review.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2020
    Article
  13. Review
  14. Review
  15. Multiple metabolic pathways are predictive of ricin intoxication in a rat model.Metabolomics : Official journal of the Metabolomic Society · 2019
    Article
  16. Biological Toxins as the Potential Tools for Bioterrorism.International journal of molecular sciences · 2019
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Gareth D GriffithsBiology Department, Defence Science and Technology Laboratory, Porton Down, Wiltshire SP4 0JQ, UK. gdgriffiths@dstl.gov.uk

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The toxin ricin has long been understood to have potential for criminal activity and there has been concern that it might be used as a mass-scale weapon on a military basis for at least two decades. Currently, the focus has extended to encompass terrorist activities using ricin to disrupt every day activities on a smaller scale. Whichever scenario is considered, there are features in common which need to be understood; these include the knowledge of the toxicity from ricin poisoning by the likely routes, methods for the detection of ricin in relevant materials and approaches to making an early diagnosis of ricin poisoning, in order to take therapeutic steps to mitigate the toxicity. This article will review the current situation regarding each of these stages in our collective understanding of ricin and how to defend against its use by an aggressor.

Indexed as

Administration, OralAnimalsChemical Warfare AgentsEatingHumansInhalation ExposureInjections, IntramuscularRicinChemical Warfare AgentsRicinantibody based testsdetectioningestioninhalationmass spectrometryparenteral (intramuscular)polymerase chain reactiontoxicology of ricin

Identifiers

PMID22174975
PMCPMC3237001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.