Evidence map›Paper›PMID 22174742›Full record

ArticlePloS one2011

The impact of focused Gene Ontology curation of specific mammalian systems.

Yasmin Alam-Faruque, Rachael P Huntley, Varsha K Khodiyar, Evelyn B Camon, Emily C Dimmer, Tony Sawford, Maria J Martin, Claire O'Donovan, Philippa J Talmud, Peter Scambler and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Shared resources, shared costs--leveraging biocuration resources.Database : the journal of biological databases and curation · 2015
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. A task-based approach for Gene Ontology evaluation.Journal of biomedical semantics · 2013
    Article
  17. Review
  18. A guide to best practices for Gene Ontology (GO) manual annotation.Database : the journal of biological databases and curation · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yasmin Alam-FaruqueEMBL-European Bioinformatics Institute, Hinxton, Cambridge, United Kingdom.
Rachael P Huntley
Varsha K Khodiyar
Evelyn B Camon
Emily C Dimmer
Tony Sawford
Maria J Martin
Claire O'Donovan
Philippa J Talmud
Peter Scambler
Rolf Apweiler
Ruth C Lovering
European Bioinformatics Institute · GBUniversity College London · GB

Funding

GENE ONTOLOGY CONSORTIUMR01HG002273 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A · 2001 to 2003
$5.8M
British Heart Foundation RG/10/13/28570British Heart Foundation SP/07/007/23671NHGRI NIH HHS R01 HG002273NHGRI NIH HHS R01HG02273-02
6 · The paper itself

Abstract

unlabelledThe Gene Ontology (GO) resource provides dynamic controlled vocabularies to provide an information-rich resource to aid in the consistent description of the functional attributes and subcellular locations of gene products from all taxonomic groups (www.geneontology.org). System-focused projects, such as the Renal and Cardiovascular GO Annotation Initiatives, aim to provide detailed GO data for proteins implicated in specific organ development and function. Such projects support the rapid evaluation of new experimental data and aid in the generation of novel biological insights to help alleviate human disease. This paper describes the improvement of GO data for renal and cardiovascular research communities and demonstrates that the cardiovascular-focused GO annotations, created over the past three years, have led to an evident improvement of microarray interpretation. The reanalysis of cardiovascular microarray datasets confirms the need to continue to improve the annotation of the human proteome. AVAILABILITY: GO ANNOTATION DATA IS FREELY AVAILABLE FROM: ftp://ftp.geneontology.org/pub/go/gene-associations/

Indexed as

AnimalsDatabases, GeneticHigh-Throughput Nucleotide SequencingHumansKidneyMacrophagesMammalsMolecular Sequence AnnotationOligonucleotide Array Sequence AnalysisStatistics as Topic

Identifiers

PMID22174742
PMCPMC3235096
OpenAlexW2019151212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.