ArticleInternational journal of dentistry2012
Local regeneration of dentin-pulp complex using controlled release of fgf-2 and naturally derived sponge-like scaffolds.
Article in International journal of dentistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Tissue Regeneration on Rise: Dental Hard Tissue Regeneration and Challenges-A Narrative Review.Scientifica · 2024Review
- Development of Growth Factor Releasing Hyaluronic Acid-Based Hydrogel for Pulp Regeneration: A Preliminary Study.Gels (Basel, Switzerland) · 2022Article
- Phenol-Grafted Alginate Sulfate Hydrogel as an Injectable FGF-2 Carrier.Gels (Basel, Switzerland) · 2022Article
- Neural Regeneration in Regenerative Endodontic Treatment: An Overview and Current Trends.International journal of molecular sciences · 2022Review
- Application of dental stem cells in three-dimensional tissue regeneration.World journal of stem cells · 2021Review
- Local Drug Delivery Systems for Vital Pulp Therapy: A New Hope.International journal of biomaterials · 2021Review
- The Regenerative Potential of bFGF in Dental Pulp Repair and Regeneration.Frontiers in pharmacology · 2021Review
- Tooth Formation: Are the Hardest Tissues of Human Body Hard to Regenerate?International journal of molecular sciences · 2020Review
- Tissue Engineering Approaches for Enamel, Dentin, and Pulp Regeneration: An Update.Stem cells international · 2020Review
- Stem cells and tooth regeneration: prospects for personalized dentistry.The EPMA journal · 2019Review
- Evaluation of Chitosan Hydrogel for Sustained Delivery of VEGF for Odontogenic Differentiation of Dental Pulp Stem Cells.Stem cells international · 2019Article
- FGF2 Enhances Odontoblast Differentiation by αSMAJournal of dental research · 2018Article
- Hyaluronic acid hydrogels incorporating platelet lysate enhance human pulp cell proliferation and differentiation.Journal of materials science. Materials in medicine · 2018Article
- Biocompatibility of two experimental scaffolds for regenerative endodontics.Restorative dentistry & endodontics · 2016Article
- Active Nanomaterials to Meet the Challenge of Dental Pulp Regeneration.Materials (Basel, Switzerland) · 2015Review
- A hyaluronan-based scaffold for the in vitro construction of dental pulp-like tissue.International journal of molecular sciences · 2015Article
- Calcium orthophosphates in dentistry.Journal of materials science. Materials in medicine · 2013Review
- Dentin and dental pulp regeneration by the patient's endogenous cells.Endodontic topics · 2013Article
- Effects of growth factors on dental stem/progenitor cells.Dental clinics of North America · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Restorative and endodontic procedures have been recently developed in an attempt to preserve the vitality of dental pulp after exposure to external stimuli, such as caries infection or traumatic injury. When damage to dental pulp is reversible, pulp wound healing can proceed, whereas irreversible damage induces pathological changes in dental pulp, eventually requiring its removal. Nonvital teeth lose their defensive abilities and become severely damaged, resulting in extraction. Development of regeneration therapy for the dentin-pulp complex is important to overcome limitations with presently available therapies. Three strategies to regenerate the dentin-pulp complex have been proposed; regeneration of the entire tooth, local regeneration of the dentin-pulp complex from amputated dental pulp, and regeneration of dental pulp from apical dental pulp or periapical tissues. In this paper, we focus on the local regeneration of the dentin-pulp complex by application of exogenous growth factors and scaffolds to amputated dental pulp.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.