Evidence map›Paper›PMID 22174304›Full record

ArticleBlood2011

Can we build a better allograft?

Steven M Devine

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Blood, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Steven M DevineThe Ohio State University Comprehensive Cancer Center.
The Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Compelling evidence has been accumulating recently implicating disruption of CXCR4/CXCL12 signaling as a key step in the mobilization of hematopoietic stem and progenitor cells (HSPCs) induced by G-CSF and other agents. This knowledge formed the rationale for the clinical development and ultimate FDA approval of a specific CXCR4 antagonist, AMD3100, for the mobilization of HSPCs in patients with non-Hodgkin lymphoma and multiple myeloma when given in combination of G-CSF.

Identifiers

PMID22174304
OpenAlexW2320322731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.