ArticleGenetics2012
Gene capture by Helitron transposons reshuffles the transcriptome of maize.
Article in Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed.
- Review
- Helitrons are enriched in lichenized fungi with long generation lengths and small distribution sizes.G3 (Bethesda, Md.) · 2026Article
- Evolutionary Study of Transposable Elements: Structural Characterization and Phylogenomic Profiling in Plant Genomes.Journal of molecular evolution · 2026Review
- Transposable elements hitchhike on Starships across fungal genomes.Nature communications · 2026Article
- Epigenetic modification brings new opportunities for gene capture by transposable elements in allopolyploidHorticulture research · 2025Article
- Impact of a horizontally transferred Helitron family on genome evolution in Xenopus laevis.Mobile DNA · 2025Article
- Discovery of numerous novel Helitron-like elements in eukaryote genomes using HELIANO.Nucleic acids research · 2024Article
- Systematic identification of cargo-mobilizing genetic elements reveals new dimensions of eukaryotic diversity.Nucleic acids research · 2024Article
- The final piece of the Triangle of U: Evolution of the tetraploid Brassica carinata genome.The Plant cell · 2022Article
- The multiple fates of gene duplications: Deletion, hypofunctionalization, subfunctionalization, neofunctionalization, dosage balance constraints, and neutral variation.The Plant cell · 2022Article
- Article
- Transcriptional activity of transposable elements along an elevational gradient in Arabidopsis arenosa.Mobile DNA · 2021Article
- Transposable element discovery and characterization of LTR-retrotransposon evolutionary lineages in the tropical fruit species Passiflora edulis.Molecular biology reports · 2019Article
- The unique epigenetic features of Pack-MULEs and their impact on chromosomal base composition and expression spectrum.Nucleic acids research · 2018Article
- Maize RNA PolIV affects the expression of genes with nearby TE insertions and has a genome-wide repressive impact on transcription.BMC plant biology · 2017Article
- Stability of Single-Parent Gene Expression Complementation in Maize Hybrids upon Water Deficit Stress.Plant physiology · 2017Article
- Horizontal transfer of a novel Helentron in insects.Molecular genetics and genomics : MGG · 2017Article
- Transposable elements inMobile genetic elements · 2017Review
- Genome Sequencing of the Phytoseiid Predatory Mite Metaseiulus occidentalis Reveals Completely Atomized Hox Genes and Superdynamic Intron Evolution.Genome biology and evolution · 2016Article
- Transposable Elements versus the Fungal Genome: Impact on Whole-Genome Architecture and Transcriptional Profiles.PLoS genetics · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helitrons are a family of mobile elements that were discovered in 2001 and are now known to exist in the entire eukaryotic kingdom. Helitrons, particularly those of maize, exhibit an intriguing property of capturing gene fragments and placing them into the mobile element. Helitron-captured genes are sometimes transcribed, giving birth to chimeric transcripts that intertwine coding regions of different captured genes. Here, we perused the B73 maize genome for high-quality, putative Helitrons that exhibit plus/minus polymorphisms and contain pieces of more than one captured gene. Selected Helitrons were monitored for expression via in silico EST analysis. Intriguingly, expression validation of selected elements by RT-PCR analysis revealed multiple transcripts not seen in the EST databases. The differing transcripts were generated by alternative selection of splice sites during pre-mRNA processing. Selection of splice sites was not random since different patterns of splicing were observed in the root and shoot tissues. In one case, an exon residing in close proximity but outside of the Helitron was found conjoined with Helitron-derived exons in the mature transcript. Hence, Helitrons have the ability to synthesize new genes not only by placing unrelated exons into common transcripts, but also by transcription readthrough and capture of nearby exons. Thus, Helitrons have a phenomenal ability to "display" new coding regions for possible selection in nature. A highly conservative, minimum estimate of the number of new transcripts expressed by Helitrons is ~11,000 or ~25% of the total number of genes in the maize genome.
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