ArticleAJNR. American journal of neuroradiology2012
The role of MR myelography with intrathecal gadolinium in localization of spinal CSF leaks in patients with spontaneous intracranial hypotension.
Article in AJNR. American journal of neuroradiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 116 citations in OpenAlex.
- The status of diagnosis and treatment to intracranial hypotension, including SIH.The journal of headache and pain · 2017Pooled it
- Spontaneous intracranial hypotension with negative brain MRI findings: a systematic review of diagnostic strategies and clinical outcomes.Frontiers in neurologyPooled it
- Recent Updates to Diagnosis and Treatment of Spontaneous Intracranial Hypotension.Korean journal of radiology · 2026Review
- Bilateral subdural hematomas in spontaneous intracranial hypotension: A systematic review with case illustration.Surgical neurology international · 2026Review
- Critical Reappraisal and Validation of the Bern Score System for Diagnosing Spontaneous Intracranial Hypotension.Journal of clinical neurology (Seoul, Korea) · 2025Article
- Notable differences in changes between ventral and dorsolateral spinal longitudinal extradural CSF collection after treatment in patients with spontaneous spinal CSF leaks.Neurosurgical review · 2025Article
- Myelographic Techniques for the Localization of CSF-Venous Fistulas: Updates in 2024.AJNR. American journal of neuroradiology · 2024Review
- Prospective Safety Study of Intrathecal Gadobutrol in Different Doses.AJNR. American journal of neuroradiology · 2023Article
- [Intracranial hypotension syndrome in a pediatric patient with Marfan syndrome].Anales del sistema sanitario de Navarra · 2023Article
- Diagnostic Yield of Intrathecal Gadolinium MR Myelography for CSF Leak Localization.Clinical neuroradiology · 2022Article
- Chronic CSF leak from lumbar-peritoneal shunt tract: A case report.Surgical neurology international · 2022Article
- Diskogenic Dural Defect Is the Reason for the Ventral Location of the Epidural Spinal Fluid Collection Seen in Superficial Siderosis.Neurology. Clinical practice · 2021Review
- CSF-Venous Fistula.Current pain and headache reports · 2021Review
- Off-label intrathecal use of gadobutrol: safety study and comparison of administration protocols.Neuroradiology · 2021Article
- Intravenous enhanced 3D FLAIR imaging to identify CSF leaks in spontaneous intracranial hypotension: Comparison with MR myelography.European journal of radiology open · 2021Article
- Spontaneous Intracranial Hypotension Complicated by Subdural Effusions Treated by Surgical Relief of Cranial Venous Outflow Obstruction.Journal of neurological surgery reports · 2020Article
- Safety of Consecutive Bilateral Decubitus Digital Subtraction Myelography in Patients with Spontaneous Intracranial Hypotension and Occult CSF Leak.AJNR. American journal of neuroradiology · 2020Article
- Spine MRI in Spontaneous Intracranial Hypotension for CSF Leak Detection: Nonsuperiority of Intrathecal Gadolinium to Heavily T2-Weighted Fat-Saturated Sequences.AJNR. American journal of neuroradiology · 2020Article
- MR Myelography for the Detection of CSF-Venous Fistulas.AJNR. American journal of neuroradiology · 2020Article
- Spinal Cerebrospinal Fluid Leakage in Spontaneous Intracranial Hypotension: An Intrathecal Gadolinium Enhanced MR-Myelography Study.Journal of the Belgian Society of Radiology · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeLocalization of spinal CSF leaks in CSF hypovolemia is critical in directing focal therapy. In this retrospective review, our aim was to determine whether GdM was helpful in confirming and localizing spinal CSF leaks in patients in whom no leak was identified on a prior CTM. MATERIALS AND
methodsForty-one symptomatic patients with clinical suspicion of SIH were referred for GdM after undergoing at least 1 CTM between February 2002 and August 2010. A retrospective review of the imaging and electronic medical records was performed on each patient.
resultsIn 17 of the 41 patients (41%), GdM was performed for follow-up of a previously documented leak at CTM. In the remaining 24 patients (59%), in whom GdM was performed for a suspected CSF leak, which was not identified on CTM, GdM localized the CSF leak in 5 of 24 patients (21%). In 1 of these 5 patients, GdM detected the site of leak despite negative findings on brain MR imaging, spine MR imaging, and CTM of the entire spine. Sixteen of 17 patients with previously identified leaks underwent interval treatment, and leaks were again identified in 12 of 17 (71%).
conclusionsGdM is a useful technique in the highly select group of patients who have debilitating symptoms of SIH, a high clinical index of suspicion of spinal CSF leak, and no demonstrated leak on conventional CTM. Intrathecal injection of gadolinium contrast remains an off-label use and should be reserved for those patients who fail conventional CTM.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.