Evidence map›Paper›PMID 22173144›Full record

ArticleThe Pediatric infectious disease journal2012

Absence of gastrointestinal pathogens in ileum tissue resected for necrotizing enterocolitis.

Tim Ullrich, Yi-Wei Tang, Hernan Correa, Steven A Garzon, Akhil Maheshwari, Melissa Hill, Pranathi Matta, Mohan K Krishnan, Jörn-Hendrik Weitkamp

Abstract read
In one paragraph

Article in The Pediatric infectious disease journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Dynamics of the preterm gut microbiome in health and disease.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Review
  7. Article
  8. Development (Cambridge, England) · 2017
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tim UllrichDepartment of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt, Vanderbilt University, Nashville, TN, USA.
Yi-Wei Tang
Hernan Correa
Steven A Garzon
Akhil Maheshwari
Melissa Hill
Pranathi Matta
Mohan K Krishnan
Jörn-Hendrik Weitkamp

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR) KL2KL2RR024977 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$3.0M
Role of Transforming Growth Factor-beta in Neonatal Necrotizing EnterocolitisR01HD059142 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MAHESHWARI, AKHIL · 2009 to 2013
$1.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR) TL1TL1RR024978 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$1.3M
Development of Intestinal Immune Regulation in Human InfantsK08HD061607 · NICHD · VANDERBILT UNIVERSITY · PI WEITKAMP, JOERN-HENDRIK · 2009 to 2013
$628k
NCRR NIH HHS KL2 RR024977NCRR NIH HHS TL1 RR024978NCRR NIH HHS UL1 RR024975NICHD NIH HHS K08 HD061607NICHD NIH HHS K08HD061607NICHD NIH HHS R01 HD059142NICHD NIH HHS R01HD059142
6 · The paper itself

Abstract

Necrotizing enterocolitis (NEC) is one of the most common gastrointestinal emergencies in premature infants and has been linked with viral antigens in as much as 40% of cases in single-center cohorts. We examined 28 tissue sections from surgically resected ileum from 27 preterm infants with NEC from 2 separate institutions for 15 common bacterial, viral, and parasitic gastrointestinal pathogens using multiplex reverse transcriptase polymerase chain reaction amplification and suspension array detection methods. We did not detect infectious enteritis pathogens in any of the NEC tissues and conclude that gastrointestinal pathogens are a rare cause of NEC.

Indexed as

AnimalsBacteriaEnterocolitis, NecrotizingFemaleHumansIleumInfantInfant, NewbornMaleMultiplex Polymerase Chain ReactionParasitesReverse Transcriptase Polymerase Chain ReactionViruses

Identifiers

PMID22173144
PMCPMC3305842

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.