ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2012
Seizure source imaging by means of FINE spatio-temporal dipole localization and directed transfer function in partial epilepsy patients.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed.
- Neurobiological mechanisms of TENS-induced analgesia.NeuroImage · 2019Trial
- Human brain imaging with high-density electroencephalography: Techniques and applications.The Journal of physiology · 2026Review
- Mapping epileptogenic brain using a unified spatial-temporal-spectral source imaging framework.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Noninvasive Seizure Onset Zone Localization Using Janashia-Lagvilava Algorithm-Based Spectral Factorization in Granger Causality.Brain sciences · 2025Article
- Performance of blind source separation in localizing seizure onset from routine scalp-EEG.Journal of neurology · 2025Article
- Article
- Deep learning-based EEG source imaging is robust under varying electrode configurations.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Electroencephalography derived connectivity informing epilepsy surgical planning: Towards clinical applications and future perspectives.NeuroImage. Clinical · 2024Review
- Disentanglement of Resting State Brain Networks for Localizing Epileptogenic Zone in Focal Epilepsy.Brain topography · 2024Article
- Concurrent interactions between prefrontal cortex and hippocampus during a spatial working memory task.Brain structure & function · 2022Article
- An Explainable Statistical Method for Seizure Prediction Using Brain Functional Connectivity from EEG.Computational intelligence and neuroscience · 2022Article
- Imaging the extent and location of spatiotemporally distributed epileptiform sources from MEG measurements.NeuroImage. Clinical · 2022Article
- Design of MRI structured spiking neural networks and learning algorithms for personalized modelling, analysis, and prediction of EEG signals.Scientific reports · 2021Article
- Noninvasive electromagnetic source imaging of spatiotemporally distributed epileptogenic brain sources.Nature communications · 2020Article
- Model-based design for seizure control by stimulation.Journal of neural engineering · 2020Article
- Computational modelling in source space from scalp EEG to inform presurgical evaluation of epilepsy.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2020Article
- Electrophysiological Brain Connectivity: Theory and Implementation.IEEE transactions on bio-medical engineering · 2019Article
- Network Perspectives on Epilepsy Using EEG/MEG Source Connectivity.Frontiers in neurology · 2019Review
- Electrophysiological Source Imaging: A Noninvasive Window to Brain Dynamics.Annual review of biomedical engineering · 2018Review
- Phase Synchronization Dynamics of Neural Network during Seizures.Computational and mathematical methods in medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveTo investigate the usage of a high-density EEG recording system and source imaging technique for localizing seizure activity in patients with medically intractable partial epilepsy.
methodsHigh-density, 76-channel scalp EEG signals were recorded in 10 patients with partial epilepsy. The patients underwent routine clinical pre-surgical evaluation and all had resective surgery with seizure free outcome. After applying a FINE (first principle vectors) spatio-temporal source localization and DTF (directed transfer function) connectivity analysis approach, ictal sources were imaged. Effects of number of scalp EEG electrodes on the seizure localization were also assessed using 76, 64, 48, 32, and 21 electrodes, respectively.
resultsSurgical resections were used to assess the source imaging results. Results from the 76-channel EEG in the 10 patients showed high correlation with the surgically resected brain regions. The localization of seizure onset zone from 76-channel EEG showed improved source detection accuracy compared to other EEG configurations with fewer electrodes.
conclusionsFINE together with DTF was able to localize seizure onset zones of partial epilepsy patients. High-density EEG recording can help achieve improved seizure source imaging. SIGNIFICANCE: The present results suggest the promise of high-density EEG and electrical source imaging for noninvasively localizing seizure onset zones.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.