Evidence map›Paper›PMID 22172540›Full record

ReviewCurrent opinion in structural biology2012

Recent advances in single molecule studies of nucleosomes.

Jessica L Killian, Ming Li, Maxim Y Sheinin, Michelle D Wang

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in structural biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Single-Molecule Techniques to Study Chromatin.Frontiers in cell and developmental biology · 2021
    Review
  7. Article
  8. Review
  9. Review
  10. DNA looping mediates nucleosome transfer.Nature communications · 2016
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jessica L KillianDepartment of Physics, Laboratory of Atomic and Solid State Physics, Cornell University, Ithaca, NY 14853, USA.
Ming Li
Maxim Y Sheinin
Michelle D Wang
Cornell University · USHoward Hughes Medical Institute · US

Funding

TRAINING IN MOLECULAR PHYSICS OF BIOLOGICAL SYSTEMST32GM008267 · NIGMS · CORNELL UNIVERSITY ITHACA · PI WANG, MICHELLE D. · 1988 to 2021
$9.6M
STUDIES OF NUCLEOSOME STABILITY AND TRANSCRIPTIONR01GM059849 · NIGMS · CORNELL UNIVERSITY ITHACA · PI WANG, MICHELLE D. · 1999 to 2008
$2.2M
Howard Hughes Medical InstituteNIGMS NIH HHS GM059849NIGMS NIH HHS R01 GM059849NIGMS NIH HHS T32 GM008267
6 · The paper itself

Abstract

As the fundamental packing units of DNA in eukaryotes, nucleosomes play a central role in governing DNA accessibility in a variety of cellular processes. Our understanding of the mechanisms underlying this complex regulation has been aided by unique structural and dynamic perspectives offered by single molecule techniques. Recent years have witnessed remarkable advances achieved using these techniques, including the generation of a detailed histone-DNA energy landscape, elucidation of nucleosome disassembly processes, and real-time monitoring of molecular motors interacting with nucleosomes. These and other highlights of single molecule nucleosome studies will be discussed in this review.

Indexed as

AnimalsDNAHistonesHumansNucleosomesTranscription, GeneticDNAHistonesNucleosomes

Identifiers

PMID22172540
PMCPMC5515226
OpenAlexW2047574014

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.