ArticleEmerging infectious diseases2011
Enterovirus co-infections and onychomadesis after hand, foot, and mouth disease, Spain, 2008.
Article in Emerging infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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45 citing papers in PubMed.
- The emerging sub-genotype C2 of CoxsackievirusA10 Associated with Hand, Foot and Mouth Disease extensively circulating in mainland of China.Scientific reports · 2018Trial
- Epidemiological, etiological, and serological characteristics of hand, foot, and mouth disease in Guizhou Province, Southwest China, from 2008 to 2023.PLoS neglected tropical diseases · 2025Article
- An outbreak of atypical hand, foot and mouth disease associated Coxsackievirus A6 in children from Cape Verde, 2023.Virology journal · 2025Article
- Changing Epidemiology of Hand, Foot, and Mouth Disease Causative Agents and Contributing Factors.The American journal of tropical medicine and hygiene · 2024Review
- Coxsackievirus A10 impairs nail regeneration and induces onychomadesis by mimicking DKK1 to attenuate Wnt signaling.The Journal of experimental medicine · 2024Article
- Single nucleotide polymorphism of Notch1 gene rs3124599 allele is associated with the severity of CVA6-related HFMD in the Chinese Han population.BMC infectious diseases · 2024Article
- Drug Repositioning for Hand, Foot, and Mouth Disease.Viruses · 2022Review
- Genomic surveillance of coxsackievirus A10 reveals genetic features and recent appearance of genogroup D in Shanghai, China, 2016-2020.Virologica Sinica · 2022Article
- Coxsackievirus A6 strains causing an outbreak of hand-foot-and-mouth disease in Northeastern Brazil in 2018.Revista do Instituto de Medicina Tropical de Sao Paulo · 2022Article
- Enterovirus Surveillance (EVSurv) in Germany.Microorganisms · 2021Article
- Article
- Development of a pseudovirus-based assay for measuring neutralizing antibodies against Coxsackievirus A10.Human vaccines & immunotherapeutics · 2020Article
- Onychomadesis and potential association with HFMD outbreak in a kindergarten in Hubei province, China, 2017.BMC infectious diseases · 2019Article
- Construction and characterization of an infectious cDNA clone of coxsackievirus A 10.Virology journal · 2019Article
- Identification of a new recombinant strain of echovirus 33 from children with hand, foot, and mouth disease complicated by meningitis in Yunnan, China.Virology journal · 2019Article
- Molecular characteristic analysis for the VP1 region of coxsackievirus A6 strains isolated in Jiujiang area, China, from 2012 to 2013.Medicine · 2019Article
- Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6: A Preliminary Report from Istanbul.Polish journal of microbiology · 2019Article
- Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.Science advances · 2018Article
- Epidemiological surveillance of hand, foot and mouth disease in Shanghai in 2014-2016, prior to the introduction of the enterovirus 71 vaccine.Emerging microbes & infections · 2018Article
- Serological survey of neutralizing antibodies to eight major enteroviruses among healthy population.Emerging microbes & infections · 2018Article
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5 authors.
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Abstract
Hand, foot, and mouth disease (HFMD), a common disease caused by enteroviruses (EVs), usually affects children. Clustered and sporadic HFMD cases, followed by onychomadesis (nail shedding), occurred during summer and fall 2008 in Valencia, Spain. Fecal samples from onychomadesis patients, who did or did not have previous HFMD, and from healthy children exposed to onychomadesis patients tested positive for EV. The complete viral protein 1 capsid gene sequence was obtained for typing and phylogenetic analysis. Two EV serotypes, coxsackievirus A10 and coxsackievirus B1 (CVB1), were mainly detected as a monoinfection or co-infection in a childcare center where an onychomadesis outbreak occurred. On the basis of our results, and detection of CVB1 in 2 other contemporary onychomadesis outbreaks in childcare centers in Spain, we propose that mixed infection of an EV serotype that causes HFMD, plus the serotype CVB1, could explain the emergence after HFMD of onychomadesis, a rare and late complication.
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