Evidence map›Paper›PMID 22172157›Full record

ArticleEmerging infectious diseases2011

Novel multiplexed HIV/simian immunodeficiency virus antibody detection assay.

Steve Ahuka-Mundeke, Ahidjo Ayouba, Placide Mbala-Kingebeni, Florian Liegeois, Amandine Esteban, Octavie Lunguya-Metila, Didace Demba, Guy Bilulu, Valentin Mbenzo-Abokome, Bila-Isia Inogwabini and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

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  5. Multiplex detection and dynamics of IgG antibodies to SARS-CoV2 and the highly pathogenic human coronaviruses SARS-CoV and MERS-CoV.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Steve Ahuka-MundekeUniversity of Montpellier, Montpellier, France.
Ahidjo Ayouba
Placide Mbala-Kingebeni
Florian Liegeois
Amandine Esteban
Octavie Lunguya-Metila
Didace Demba
Guy Bilulu
Valentin Mbenzo-Abokome
Bila-Isia Inogwabini
Jean-Jacques Muyembe-Tamfum
Eric Delaporte
Martine Peeters
National Institute of Biomedical Research · CDUniversité de Montpellier · FR

Funding

Natural SIV Reservoirs and Human Zoonotic RiskR01AI050529 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2001 to 2022
$6.1M
NIAID NIH HHS R01 AI050529NIAID NIH HHS R01 AI 50529
6 · The paper itself

Abstract

Like most emerging infectious disease viruses, HIV is also of zoonotic origin. To assess the risk for cross-species transmission of simian immunodeficiency viruses (SIVs) from nonhuman primates to humans in the Democratic Republic of Congo, we collected 330 samples derived from nonhuman primate bushmeat at 3 remote forest sites. SIV prevalences were estimated by using a novel high-throughput assay that included 34 HIV and SIV antigens in a single well. Overall, 19% of nonhuman primate bushmeat was infected with SIVs, and new SIV lineages were identified. Highest SIV prevalences were seen in red-tailed guenons (25%) and Tshuapa red colobus monkeys (24%), representing the most common hunted primate species, thus increasing the likelihood for cross-species transmission. Additional studies are needed to determine whether other SIVs crossed the species barrier. With the newly developed assay, large-scale screening against many antigens is now easier and faster.

Indexed as

Amino Acid SequenceAnimalsAntibodies, ViralBase SequenceColobusCommunicable Diseases, EmergingCross ReactionsDemocratic Republic of the CongoDNA, Z-FormGenetic VariationHigh-Throughput Screening AssaysHIV-1HIV AntibodiesHIV AntigensHIV InfectionsHumansAntibodies, ViralDNA, Z-FormHIV AntibodiesHIV AntigensRetroviridae Proteins

Identifiers

PMID22172157
PMCPMC3311211
OpenAlexW2004222410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.