Evidence map›Paper›PMID 22171825›Full record

ArticleJournal of the American Chemical Society2012

Compositional control of higher order assembly using synthetic collagen peptides.

Fei Xu, Ji Li, Vikas Jain, Raymond S Tu, Qingrong Huang, Vikas Nanda

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Recombinant collagen hydrogels induced by disulfide bonds.Journal of biomedical materials research. Part A · 2022
    Article
  4. Article
  5. Article
  6. How electrostatic networks modulate specificity and stability of collagen.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  7. Multicomponent peptide assemblies.Chemical Society reviews · 2018
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fei XuDepartment of Biochemistry, Robert Wood Johnson Medical School, UMDNJ and the Center for Advanced Biotechnology and Medicine, Piscataway, New Jersey 08854, USA.
Ji Li
Vikas Jain
Raymond S Tu
Qingrong Huang
Vikas Nanda

Funding

Computational Design of a Synthetic Extracellular MatrixDP2OD006478 · OD · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI NANDA, VIKAS · 2009 to 2009
$2.3M
NIH HHS DP2 OD006478NIH HHS DP2 OD006478-01
6 · The paper itself

Abstract

We present the case of a two-component collagen peptide hydrogel that self-assembles through noncovalent electrostatic interactions. Natural collagen materials, such as those of connective tissue or the basement membrane, assemble in a hierarchic fashion. Similarly, the synthetic peptides presented here proceed from monomer to trimer to fiber and, finally, to a hydrogel. By varying stoichiometry and concentration, we are able to dissect the stages of higher order assembly. Insight gained from this study will improve the molecular design of biomimetic materials.

Indexed as

Biocompatible MaterialsCollagenDrug CarriersHydrogelsPeptide FragmentsProtein MultimerizationStatic ElectricityBiocompatible MaterialsCollagenDrug CarriersHydrogelsPeptide Fragments

Identifiers

PMID22171825
PMCPMC3443862

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.