Evidence map›Paper›PMID 22170815›Full record

ArticleCytometry. Part A : the journal of the International Society for Analytical Cytology2012

Identification of a cross-reacting, monoclonal anti-human CD233 antibody for identification and sorting of rhesus macaque erythrocytes.

Colleen Byrnes, Y Terry Lee, Robert E Donahue, Jeffery L Miller

Abstract read
In one paragraph

Article in Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Colleen ByrnesMolecular Medicine Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
Y Terry Lee
Robert E Donahue
Jeffery L Miller

Funding

Retroviral Mediated Gene Transfer Into Primate Hematopoietic CellsZICHL002338 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI DONAHUE, ROBERT E · 2010 to 2018
$30.5M
Research Studies of Erythropoiesis and Iron Biology.ZIADK025098 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI MILLER, JEFFERY · 2009 to 2016
$6.3M
Intramural NIH HHS ZIA DK025098
6 · The paper itself

Abstract

Erythroid biology research involving rhesus macaques has been applied to several topics including malaria, hemoglobinopathy and gene therapy research. However, analyses of the rhesus red blood cells are limited by the inability to identify and sort those cells in research blood samples using flow cytometry. Here it is reported that the BRIC 6 hybridoma clone raised to the human erythroid surface molecule (referred to as CD233, Band 3, AE1, or SLC4A1) produces cross-reactive and erythroid-specific antibodies for flow cytometric detection and sorting of rhesus macaque erythrocytes.

Indexed as

Amino Acid SequenceAnimalsAnion Exchange Protein 1, ErythrocyteAntibodies, MonoclonalCross ReactionsErythrocytesFlow CytometryGlycophorinsHumansMacaca mulattaMolecular Sequence DataAnion Exchange Protein 1, ErythrocyteAntibodies, MonoclonalGlycophorinsSLC4A1 protein, human

Identifiers

PMID22170815
PMCPMC4528389

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.