ArticlePediatric pulmonology2012
A study of the use of impulse oscillometry in the evaluation of children with asthma: analysis of lung parameters, order effect, and utility compared with spirometry.
Article in Pediatric pulmonology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Oscillometry for the diagnosis of asthma in children: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- Peripheral Airway Dysfunction Assessed by Impulse Oscillometry in School-Aged Children Born Preterm: A Cross-Sectional Comparative Study.Journal of clinical medicine · 2026Article
- Prenatal PMRespirology (Carlton, Vic.) · 2026Article
- Small Airway Dysfunction Assessed by Impulse Oscillometry in Non-Asthmatic Children with Moderate-to-Severe Persistent Allergic Rhinitis During the Early Phase of Allergen Immunotherapy.Journal of clinical medicine · 2026Article
- Clinical Utility of Impulse Oscillometry Parameters in Predicting Asthma Exacerbations.Tuberculosis and respiratory diseases · 2026Article
- Impulse oscillometry values calibrated against spirometric obstruction in children with suspected asthma.Frontiers in pediatrics · 2026Article
- Bronchodilator Response of TEV/FEV3 and Its Implications in Pediatric Asthma.Allergy, asthma & immunology research · 2025Article
- Predictors of Bronchodilator Response on Oscillometry and Spirometry in School-Age Children With Bronchopulmonary Dysplasia.Pediatric pulmonology · 2025Observational
- Changes in airway resistance and its correlation with disease severity in children withTranslational pediatrics · 2025Article
- Early childhood lower-airway symptoms and airway hyperresponsiveness linked to school-age small-airway dysfunction.The journal of allergy and clinical immunology. Global · 2025Article
- Preschool impulse oscillometry predicts active asthma and impaired lung function at school age.The Journal of allergy and clinical immunology · 2024Article
- Pediatric asthma and altitude: a complex interplay between different environmental factors.Italian journal of pediatrics · 2024Review
- Small airway function in predicting asthma control in preschool children.Pediatric discovery · 2024Article
- Predictive Value of Impulse Oscillometry Combined with Fractional Expiratory Nitric Oxide Test for Asthma in Preschool Children.Journal of asthma and allergy · 2024Article
- Validity of fractional exhaled nitric oxide and small airway lung function measured by IOS in the diagnosis of cough variant asthma in preschool children with chronic cough.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023Article
- Pulmonary outcomes of congenital diaphragmatic hernia patients based on defect size (CDH Study Group Stage).Translational pediatrics · 2023Article
- Lung Function Tests in Infants and Children.Indian journal of pediatrics · 2023Review
- Article
- Impulse Oscillometry System for the Diagnosis of Wheezing Episode in Children in Office Practice.Journal of asthma and allergy · 2022Article
- Infant Nasopharyngeal Microbiota Subphenotypes and Early Childhood Lung Function: Evidence from a Rural Ghanaian Pregnancy Cohort.International journal of environmental research and public health · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundThe ability to objectively measure lung function in children is critical in the assessment and treatment of asthma in this age group. We thus determined the effectiveness of impulse oscillometry (IOS) as a non-invasive technique to assess lung function in children and in comparison to spirometry for sensitivity and specificity, testing variability, and the order effect of sequential testing of IOS and spirometry.
methodsOne hundred seventeen children sequentially evaluated in a pediatric clinic and under medical care for disease, were asked to perform IOS and spirometry. The utility of IOS and spirometry in differentiating children that had asthma versus those children who did not was then analyzed.
resultsIn the primary analysis (n = 117), bronchodilator response using IOS distinguished asthmatics from non-asthmatics, P = 0.0008 for R10. Receiver-operator characteristic curve (ROC) analysis of R10 bronchodilator response at the best cut-off (-8.6% change) correctly identified 77% of patients with asthma and excluded 76% of non-asthmatics. Amongst those children able to perform spirometry (asthmatics, n = 66; non-asthmatics, n = 16), FEV(1) did not reveal a difference between these two groups, while area of reactance (AX) did distinguish these groups (P = 0.0092). Sequential testing of IOS and then spirometry (n = 47) showed a significant decrement in lung function as determined by IOS following performance of spirometry (P = 0.0309).
conclusionIn the diagnosis and management of children with lung disease, IOS is a non-invasive approach that easily and objectively measures lung impedance and should be considered as both an adjunct, and in some situations, an alternative to standard spirometry.
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