ReviewNeuromolecular medicine2012
Neurobiology and neuropathophysiology of obstructive sleep apnea.
Review in Neuromolecular medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 35 citations in OpenAlex.
- Trial
- Article
- Chronic intermittent hypoxia attenuates noradrenergic innervation of hypoglossal motor nucleus.Respiratory physiology & neurobiology · 2024Article
- Article
- Interhemispheric sleep depth coherence predicts driving safety in sleep apnea.Journal of sleep research · 2021Article
- Neuroanatomical Basis of State-Dependent Activity of Upper Airway Muscles.Frontiers in neurology · 2018Review
- SLEEP AND CIRCADIAN RHYTHM DISORDERS IN PARKINSON'S DISEASE.Current sleep medicine reports · 2017Article
- Obstructive Sleep Apnoea and Hypertension: the Role of the Central Nervous System.Current hypertension reports · 2016Review
- Combined effect of obstructive sleep apnea and chronic smoking on cognitive impairment.Sleep & breathing = Schlaf & Atmung · 2016Article
- The Interaction between Obstructive Sleep Apnea and Parkinson's Disease: Possible Mechanisms and Implications for Cognitive Function.Parkinson's disease · 2015Review
- Article
- The effect of obesity on brain diffusion alteration in patients with obstructive sleep apnea.TheScientificWorldJournal · 2014Article
- Malfolded protein structure and proteostasis in lung diseases.American journal of respiratory and critical care medicine · 2014Article
- Long-term intermittent hypoxia elevates cobalt levels in the brain and injures white matter in adult mice.Sleep · 2013Article
- Article
- Article
- The association of sleep disordered breathing with heart failure and other cardiovascular conditions.Cardiology research and practice · 2013Review
- Cerebrovascular consequences of obstructive sleep apnea.Journal of the American Heart Association · 2012Article
- Making sense of oxidative stress in obstructive sleep apnea: mediator or distracter?Frontiers in neurology · 2012Article
- Piecing together phenotypes of brain injury and dysfunction in obstructive sleep apnea.Frontiers in neurology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Significant advancements have been made over the past three decades to better understand the disease entity of obstructive sleep apnea and the mechanisms by which this prevalent disorder imparts injury. Once considered a disorder of reversible sleepiness and insignificant arterial oxygen desaturations because of their intermittency, obstructive sleep apnea is now considered an independent risk factor for cardiovascular morbidity and mortality and an important contributor to neurocognitive impairment and neural injury as well as metabolic dysfunction. The rapidly fluctuating oxygen patterns are now believed to be central to oxidative injury in the brain and peripheral organs. Recent studies in both humans with sleep apnea and animal models of the disorder have increased our understanding of the molecular mechanisms underlying both the disorder and its sequelae, providing great insight into the significance of the disorder and bringing us closer to finding therapies to prevent or reduce both obstructive sleep apnea and it morbidities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.