Polymers for gene delivery: Charged for success.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

21 citing papers in PubMed.

1. Polymeric Gene Delivery at Sub-Stoichiometric N/P Ratios.Polymer science & technology (Washington, D.C.) · 2026
   Article
2. A Serum Resistant Polymer with Exceptional Endosomal Escape and mRNA Delivery Efficacy for CRISPR Gene Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
   Article
3. Landscape of small nucleic acid therapeutics: moving from the bench to the clinic as next-generation medicines.Signal transduction and targeted therapy · 2025
   Review
4. Role of Hydrophobic Modification in Spermine-Based Poly(β-amino ester)s for siRNA Delivery and Their Spray-Dried Powders for Inhalation and Improved Storage.Biomacromolecules · 2024
   Article
5. Systematic Investigation of Biocompatible Cationic Polymeric Nucleic Acid Carriers for Immunotherapy of Hepatocellular Carcinoma.Cancers · 2021
   Review
6. Zwitterionic Phospholipidation of Cationic Polymers Facilitates Systemic mRNA Delivery to Spleen and Lymph Nodes.Journal of the American Chemical Society · 2021
   Article
7. Aliphatic Quaternary Ammonium Functionalized Nanogels for Gene Delivery.Pharmaceutics · 2021
   Article
8. Cationic Nanomaterials for Autoimmune Diseases Therapy.Frontiers in pharmacology · 2021
   Review
9. Folic Acid/Peptides Modified PLGA-PEI-PEG Polymeric Vectors as Efficient Gene Delivery Vehicles: Synthesis, Characterization and Their Biological Performance.Molecular biotechnology · 2021
   Article
10. Treatment of severe sepsis with nanoparticulate cell-free DNA scavengers.Science advances · 2020
    Article
11. Biodegradable Polymers for Gene Delivery.Molecules (Basel, Switzerland) · 2019
    Review
12. Non-viral transfection vectors: are hybrid materials the way forward?MedChemComm · 2019
    Review
13. Targeted nonviral gene therapy in prostate cancer.International journal of nanomedicine · 2018
    Review
14. Injectable nanofibrous spongy microspheres for NR4A1 plasmid DNA transfection to reverse fibrotic degeneration and support disc regeneration.Biomaterials · 2017
    Article
15. Local Delivery of CTGF siRNA with Poly(sorbitol-co-PEI) Reduces Scar Contraction in Cutaneous Wound Healing.Tissue engineering and regenerative medicine · 2017
    Article
16. Catalytic self-assembly of a DNA dendritic complex for efficient gene silencing.Chemical communications (Cambridge, England) · 2016
    Article
17. Influence of oligospermines architecture on their suitability for siRNA delivery.Biomacromolecules · 2014
    Article
18. Insight into polycation chain length affecting transfection efficiency by O-methyl-free N,N,N-trimethyl chitosans as gene carriers.Pharmaceutical research · 2014
    Article
19. Synthesis and characterization of glycol chitosan DNA nanoparticles for retinal gene delivery.ChemMedChem · 2014
    Article
20. Applications of polymeric adjuvants in studying autoimmune responses and vaccination against infectious diseases.Journal of the Royal Society, Interface · 2013
    Review

Corrections and comments

• Comment on
  Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery.2011

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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