Evidence map›Paper›PMID 22168783›Full record

ArticleInternational wound journal2012

Prevalence of immune disease in patients with wounds presenting to a tertiary wound healing centre.

Victoria K Shanmugam, Amber Schilling, Anthony Germinario, Mihriye Mete, Paul Kim, John Steinberg, Christopher E Attinger

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in International wound journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Approach to the Atypical Wound.American journal of clinical dermatology · 2024
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. A 66-Year-Old Woman With Hemoptysis.Arthritis care & research · 2017
    Article
  13. Review
  14. Vasculitic and autoimmune wounds.Journal of vascular surgery. Venous and lymphatic disorders · 2017
    Review
  15. Relationship between opioid treatment and rate of healing in chronic wounds.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2017
    Observational
  16. Article
  17. Article
  18. Postoperative wound dehiscence: Predictors and associations.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Victoria K ShanmugamDivision of Rheumatology, Immunology and Allergy, Georgetown University Hospital, Washington, DC 20007, USA. vks4@gunet.georgetown.edu
Amber Schilling
Anthony Germinario
Mihriye Mete
Paul Kim
John Steinberg
Christopher E Attinger
Georgetown University · USMedStar Health · US

Funding

Georgetown-Howard Universities Center for Clinical and Translational Science (GHUUL1RR031975 · NCRR · GEORGETOWN UNIVERSITY · PI VERBALIS, JOSEPH G · 2010 to 2011
$14.6M
Georgetown-Howard Universities Center for Clinical and Translational Science (GHUKL2RR031974 · NCRR · GEORGETOWN UNIVERSITY · PI VERBALIS, JOSEPH G · 2010 to 2011
$711k
NCRR NIH HHS KL2 RR031974NCRR NIH HHS KL2RR031974NCRR NIH HHS UL1RR031975
6 · The paper itself

Abstract

Chronic leg ulcers are a significant cause of morbidity and mortality and account for considerable healthcare and socioeconomic costs. Leg ulcers are a recognised complication of immune disease, and the purpose of this study was to establish the prevalence of immune disease in a cohort of patients with chronic wounds, and to compare wound outcomes in the subjects with and without immune disease. Retrospective chart review was completed on consecutive patients scheduled with the plastic surgeon in the Georgetown University Center for Wound Healing between 1 January 2009 and 31 March 2009. Of the 520 patients scheduled for appointments, 340 were eligible for inclusion. The prevalence of immune disease was higher than expected with 78 of 340 patients (23%) having associated immune disease. At presentation, wounds in patients with immune disease had a significantly larger mean surface area [33·4 cm(2) (69·05) compared to 22·5 cm(2) (63·65), P = 0·02]. Split thickness skin graft (STSG) and bioengineered alternative tissue (BAT) graft data was available on 177 grafts from 55 subjects. There was a significantly lower response rate to STSG in subjects with immune disease (50% compared to 97%, P = 0·0002), but response rates to BAT were not different. The association between immune diseases and chronic wounds may provide unique insights into pathways of wound healing, and warrants further study.

Indexed as

Immunocompromised HostAdultAgedAged, 80 and overAge DistributionChi-Square DistributionChronic DiseaseCohort StudiesDatabases, FactualDebridementFemaleFollow-Up StudiesHumansImmune System DiseasesLeg UlcerMale

Identifiers

PMID22168783
PMCPMC3374888
OpenAlexW2134792012

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.